Evidence map›Paper›PMID 33771279›Full record

Trial reportJournal of substance abuse treatment2021

Substance use predictors of attendance among veterans in integrated PTSD and alcohol use disorder treatment.

Alexander C Kline, Elizabeth Straus, Robert C Lyons, Abigail C Angkaw, Brittany C Davis, Moira Haller, Denise Hien, Sonya B Norman

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Alexander C KlineVA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA. Electronic address: alexander.kline@va.gov.
Elizabeth StrausVA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA.
Robert C LyonsSan Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, USA.
Abigail C AngkawVA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, USA; National Center for PTSD, 163 Veterans Drive, White River Junction, VT 05009, USA.
Brittany C DavisJames A. Haley Veterans Hospital, 13000 Bruce B. Downs Boulevard, Tampa, FL 33612, USA; Department of Psychiatry and Behavioral Neurosciences, University of South Florida, 3515 E. Fletcher Avenue, Tampa, FL 33613, USA.
Moira HallerVA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA.
Denise HienCenter of Alcohol & Substance Use Studies, Rutgers University, 607 Allison Road, New Brunswick, NJ 08854, USA.
Sonya B NormanVA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92037, USA; National Center for PTSD, 163 Veterans Drive, White River Junction, VT 05009, USA.
University of California, San Diego · USVA San Diego Healthcare System · USRutgers, The State University of New Jersey · USSan Diego State University · USUniversity of South Florida · US

Funding

Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
CSRD VA I01 CX000756NIAAA NIH HHS T32 AA013525
6 · The paper itself

Abstract

Comorbid post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) is common, defined by greater severity and impairment than either disorder alone, and associated with poor treatment attendance. Exposure therapies are effective in treating PTSD+AUD, yet substance use is still cited as a potential contraindication for exposure. This study examined substance use-related predictors of session attendance among veterans (N = 119) randomized to receive integrated exposure therapy (Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure [COPE]; Back et al., 2015) or integrated coping skills therapy (Seeking Safety [SS]; Najavits, 2002) in a clinical trial for comorbid PTSD+AUD (Norman et al., 2019). At baseline, greater percentage of heavy drinking days (β = -0.23, p = .011) and greater AUD severity per structured clinical interview for DSM-IV-TR (β = -0.21, p = .019) predicted fewer sessions across both treatments. Treatment type did not moderate the relationship between predictors and attendance, except for a trend for craving (p = .057), where greater craving predicted fewer sessions in SS (β = -0.31, p = .02) but not COPE (β = 0.14, p = .28). Percentage of abstinence days, AUD duration, and living in a controlled environment (e.g., recovery home) at the start of therapy were not associated with attendance in either treatment condition. Only a subset of substance use characteristics predicted attendance. Findings did not support the notion that alcohol use leads to lower attendance in exposure therapy compared to nonexposure therapy.

Indexed as

AlcoholismImplosive TherapyStress Disorders, Post-TraumaticSubstance-Related DisordersVeteransHumansTreatment OutcomeAlcohol useIntegrated treatmentPTSDSubstance useTreatment attendanceTreatment dropout

Identifiers

PMID33771279
PMCPMC10197953
OpenAlexW3118965045

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.