Evidence map›Paper›PMID 33771102›Full record

Trial reportBMC pregnancy and childbirth2021

The influence of exercise during pregnancy on racial/ethnic health disparities and birth outcomes.

Madigan J Raper, Samantha McDonald, Carol Johnston, Christy Isler, Edward Newton, Devon Kuehn, David Collier, Nicholas T Broskey, Adrienne Muldrow, Linda E May

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Exercise during pregnancy Dose: Influence on preterm birth outcomes.European journal of obstetrics, gynecology, and reproductive biology · 2024
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Madigan J RaperDepartment of Business, East Carolina University (ECU), 1851 MacGregor Downs Rd, MS#701, Greenville, NC, 27834, USA.
Samantha McDonaldDepartment of Kinesiology and Recreation, Illinois State University, Normal, IL, USA.
Carol JohnstonDepartment of Human Development and Family Science, ECU, Greenville, NC, USA.
Christy IslerDepartment of Obstetrics and Gynecology, ECU, Greenville, NC, USA.
Edward NewtonDepartment of Obstetrics and Gynecology, ECU, Greenville, NC, USA.
Devon KuehnDepartment of Pediatrics, ECU, Greenville, NC, USA.
David CollierDepartment of Pediatrics, ECU, Greenville, NC, USA.
Nicholas T BroskeyDepartment of Kinesiology, ECU, Greenville, NC, USA.
Adrienne MuldrowDepartment of Communication, ECU, Greenville, NC, USA.
Linda E MayDepartment of Kinesiology, ECU, Greenville, NC, USA. mayl@ecu.edu.
East Carolina University · USIllinois State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-Hispanic black (NHB) pregnant women disproportionately experience adverse birth outcomes compared to Non-Hispanic white (NHW) pregnant women. The positive effects of prenatal exercise on maternal and neonatal health may mitigate these disparities. This study evaluated the influence of prenatal exercise on racial/ethnic disparities in gestational age (GA), birthweight (BW), and risks of preterm birth (PTB), cesarean section (CS), and low-birthweight (LBW) neonates.

methodsThis study performed a secondary data analysis using data from a 24-week, two-arm exercise intervention trial (ENHANCED by Mom). Women with singleton pregnancies (< 16 weeks), aged 18-40 years, BMI between 18.5-34.99 kg/m

resultsParticipants with complete data (n = 125) were eligible for analyses (EX: n = 58, CON: n = 67). NHB pregnant women delivered lighter neonates (β = - 0.43 kg, 95% CI: - 0.68, - 0.18, p = 0.001). After adjusting for prenatal exercise, racial/ethnic disparities in BW were reduced (β = - 0.39 kg, 95% CI: - 0.65, - 0.13, p = 0.004). Prenatal exercise reduced borderline significant racial/ethnic disparities in PTB (p = 0.053) and GA (p = 0.07) with no effects found for CS and LBW.

conclusionsThe findings of this study demonstrate that prenatal exercise may attenuate the racial/ethnic disparities observed in neonatal BW, and possibly GA and PTB. Larger, diverse samples and inclusion of maternal biomarkers (e.g., cytokines) are encouraged to further evaluate these relationships.

Indexed as

Health Status DisparitiesAdolescentAdultBlack or African AmericanCesarean SectionExercise TherapyFemaleHumansInfant HealthInfant, Low Birth WeightInfant, NewbornPregnancyPremature BirthTreatment OutcomeWhite PeopleYoung AdultExerciseHealth disparitiesMaternalRace

Identifiers

PMID33771102
PMCPMC8004415
OpenAlexW3137218810

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.