Evidence map›Paper›PMID 33771065›Full record

SynthesisThe Journal of international medical research2021

Association between serum visfatin levels and psoriasis and their correlation with disease severity: a meta-analysis.

Qian Zou, Jiawei Si, Yatao Guo, Jiayu Yu, Huijuan Shi

Abstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. The Role of Adipokines in the Pathogenesis of Psoriasis.International journal of molecular sciences · 2023
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qian ZouDepartment of Clinical Medicine, Ningxia Medical University, Ningxia, China.ORCID https://orcid.org/0000-0001-6562-7945
Jiawei SiDepartment of Clinical Medicine, Ningxia Medical University, Ningxia, China.ORCID https://orcid.org/0000-0002-9299-3657
Yatao GuoDepartment of Clinical Medicine, Ningxia Medical University, Ningxia, China.ORCID https://orcid.org/0000-0002-1264-6955
Jiayu YuDepartment of Clinical Medicine, Ningxia Medical University, Ningxia, China.ORCID https://orcid.org/0000-0003-2573-8741
Huijuan ShiDepartment of Dermatovenereology, General Hospital of Ningxia Medical University, Ningxia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the association between serum visfatin levels and psoriasis and to evaluate the correlation between serum visfatin levels and the severity of psoriasis.

methodsThe electronic databases PubMed®, Embase® and the Cochrane Library were searched for articles published from inception to 1 May 2020. Data were extracted and then standard mean differences (SMDs) and 95% confidence intervals (CIs) were calculated for pooled estimates.

resultsA total of 11 studies met the inclusion criteria and were included (448 patients diagnosed with psoriasis and 377 controls). This meta-analysis demonstrated that patients with psoriasis had significantly higher levels of visfatin than the controls (SMD = 0.90, 95% CI 0.52, 1.28). Subgroup analyses showed that differences in serum visfatin levels between the patient group and the control group were associated with ethnicity, Psoriasis Area and Severity Index (PASI) and body mass index. Additionally, a meta-analysis of correlations showed that visfatin levels in patients with psoriasis were positively correlated with PASI (

conclusionsThis meta-analysis showed that serum visfatin levels in patients with psoriasis were significantly higher than those in the controls and a positive correlation between serum visfatin levels and psoriasis severity was observed.

Indexed as

Nicotinamide PhosphoribosyltransferasePsoriasisBody Mass IndexCase-Control StudiesHumansSeverity of Illness IndexNicotinamide Phosphoribosyltransferasedisease severitymeta-analysispsoriasisSerumvisfatin

Identifiers

PMID33771065
PMCPMC8168054

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.