Evidence map›Paper›PMID 33770774›Full record

ReviewPhysics in medicine and biology2021

Advanced Monte Carlo simulations of emission tomography imaging systems with GATE.

David Sarrut, Mateusz Bała, Manuel Bardiès, Julien Bert, Maxime Chauvin, Konstantinos Chatzipapas, Mathieu Dupont, Ane Etxebeste, Louise M Fanchon, Sébastien Jan and 24 more

Abstract readReview
In one paragraph

Review in Physics in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
  2. Article
  3. Design and validation of a deep learning GAN for predictingJournal of applied clinical medical physics · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  14. Article
  15. Design and Evaluation of a Portable Pinhole SPECT System forDiagnostics (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

David SarrutUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U1294, INSA-Lyon, Université Lyon 1, Lyon, France.ORCID 0000-0002-4854-4141
Mateusz BałaJagiellonian University, Kraków, Poland.
Manuel BardièsCancer Research Institute of Montpellier, U1194 INSERM/ICM/Montpellier University, 208 Av des Apothicaires, F-34298 Montpellier cedex 5, France.
Julien BertLaTIM, INSERM UMR 1101, IBRBS, Faculty of Medicine, Univ Brest, 22 avenue Camille Desmoulins, F-29238, Brest, France.
Maxime ChauvinCRCT, UMR 1037, INSERM, Université Toulouse III Paul Sabatier, Toulouse, France.ORCID 0000-0003-1999-2161
Konstantinos ChatzipapasBioemission Technology Solutions (BIOEMTECH), Alexandras Av. 116, Athens, Greece.ORCID 0000-0003-4006-9304
Mathieu DupontAix-Marseille Univ, CNRS/IN2P3, CPPM, Marseille, France.ORCID 0000-0001-5228-5608
Ane EtxebesteUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U1294, INSA-Lyon, Université Lyon 1, Lyon, France.ORCID 0000-0001-6280-9268
Louise M FanchonDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, United States of America.
Sébastien JanUniversité Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Service Hospitalier Frédéric Joliot, F-91401, Orsay, France.
Gunjan KayalCRCT, UMR 1037, INSERM, Université Toulouse III Paul Sabatier, Toulouse, France.
Assen S KirovDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, United States of America.ORCID 0000-0001-6521-3582
Paweł KowalskiHigh Energy Physics Division, National Centre for Nuclear Research, Otwock-Świerk, Poland.ORCID 0000-0002-3545-3865
Wojciech KrzemienHigh Energy Physics Division, National Centre for Nuclear Research, Otwock-Świerk, Poland.
Joey LabourUniversité de Lyon, CREATIS, CNRS UMR5220, Inserm U1294, INSA-Lyon, Université Lyon 1, Lyon, France.ORCID 0000-0002-5602-3178
Mirjam LenzFH Aachen University of Applied Sciences, Forschungszentrum Jülich, Jülich, Germany.
George LoudosBioemission Technology Solutions (BIOEMTECH), Alexandras Av. 116, Athens, Greece.
Brahim MehadjiAix-Marseille Univ, CNRS/IN2P3, CPPM, Marseille, France.
Laurent MénardUniversité Paris-Saclay, CNRS/IN2P3, IJCLab, F-91405 Orsay, France.
Christian MorelAix-Marseille Univ, CNRS/IN2P3, CPPM, Marseille, France.ORCID 0000-0001-5359-6504
Panagiotis PapadimitroulasBioemission Technology Solutions (BIOEMTECH), Alexandras Av. 116, Athens, Greece.ORCID 0000-0002-5981-6149
Magdalena RafecasInstitute of Medical Engineering, University of Lübeck, Lübeck, Germany.
Julien SalvadoriDepartment of Nuclear Medicine and Nancyclotep molecular imaging platform, CHRU-Nancy, Université de Lorraine, F-54000, Nancy, France.
Daniel SeiterDepartment of Medical Physics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, United States of America.
Mariele StockhoffMedical Image and Signal Processing (MEDISIP), Ghent University, Ghent, Belgium.ORCID 0000-0003-2835-5498
Etienne TestaUniv. Lyon, Univ. Claude Bernard Lyon 1, CNRS/IN2P3, IP2I Lyon, F-69622, Villeurbanne, France.
Carlotta TrigilaDepartment of Biomedical Engineering, University of California, Davis, CA 95616 United States of America.ORCID 0000-0002-0414-9369
Uwe PietrzykFaculty of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany.
Stefaan VandenbergheMedical Image and Signal Processing (MEDISIP), Ghent University, Ghent, Belgium.
Marc-Antoine VerdierUniversité Paris-Saclay, CNRS/IN2P3, IJCLab, F-91405 Orsay, France.
Dimitris VisvikisLaTIM, INSERM UMR 1101, IBRBS, Faculty of Medicine, Univ Brest, 22 avenue Camille Desmoulins, F-29238, Brest, France.
Karl ZiemonsFH Aachen University of Applied Sciences, Forschungszentrum Jülich, Jülich, Germany.ORCID 0000-0001-5744-7290
Milan ZvolskýInstitute of Medical Engineering, University of Lübeck, Lübeck, Germany.ORCID 0000-0003-4300-0871
Emilie RoncaliDepartment of Biomedical Engineering, University of California, Davis, CA 95616 United States of America.ORCID 0000-0002-2439-1064

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
New optical Monte Carlo simulation tools for nuclear medicineR01EB027130 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RONCALI, EMILIE · 2019 to 2023
$1.5M
Modeling of Light Transport in Nuclear Medicine Scintillation DetectorsR03EB020097 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RONCALI, EMILIE · 2015 to 2016
$157k
NCI NIH HHS P30 CA008748NIBIB NIH HHS R01 EB027130NIBIB NIH HHS R03 EB020097
6 · The paper itself

Abstract

Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand and create innovative emission tomography systems. In this paper, we reviewed the recent developments that have been proposed to simulate modern detectors and provide a comprehensive report on imaging systems that have been simulated and evaluated in GATE. Additionally, some methodological developments that are not specific for imaging but that can improve detector modeling and provide computation time gains, such as Variance Reduction Techniques and Artificial Intelligence integration, are described and discussed.

Indexed as

Artificial IntelligenceSoftwareComputer SimulationMonte Carlo MethodTomography, X-Ray ComputedCompton CameraMonte Carlo simulationPositron emission tomographySingle-photon emission computed tomography

Identifiers

PMID33770774
PMCPMC10549966

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.