Evidence map›Paper›PMID 33770405›Full record

ArticleAdvances in experimental medicine and biology2021

Amino Acid Nutrition and Metabolism in Chickens.

Wenliang He, Peng Li, Guoyao Wu

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
70.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 115 citations in OpenAlex.

  1. Trial
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  12. Amino Acid Nutrition in Poultry: A Review.Animals : an open access journal from MDPI · 2025
    Review
  13. Attrition of amino acids in the life span of broiler chickens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Review
  14. Article
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  20. L-serine metabolic regulation and host respiratory homeostasis.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wenliang HeDepartment of Animal Science, Texas A&M University, College Station, TX, USA.
Peng LiNorth American Renderers Association, Alexandria, VA, USA.
Guoyao WuDepartment of Animal Science, Texas A&M University, College Station, TX, USA. g-wu@tamu.edu.
Texas A&M University · USNorth American Renderers Association · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both poultry meat and eggs provide high-quality animal protein [containing sufficient amounts and proper ratios of amino acids (AAs)] for human consumption and, therefore, play an important role in the growth, development, and health of all individuals. Because there are growing concerns about the suboptimal efficiencies of poultry production and its impact on environmental sustainability, much attention has been paid to the formulation of low-protein diets and precision nutrition through the addition of low-cost crystalline AAs or alternative sources of animal-protein feedstuffs. This necessitates a better understanding of AA nutrition and metabolism in chickens. Although historic nutrition research has focused on nutritionally essential amino acids (EAAs) that are not synthesized or are inadequately synthesized in the body, increasing evidence shows that the traditionally classified nutritionally nonessential amino acids (NEAAs), such as glutamine and glutamate, have physiological and regulatory roles other than protein synthesis in chicken growth and egg production. In addition, like other avian species, chickens do not synthesize adequately glycine or proline (the most abundant AAs in the body but present in plant-source feedstuffs at low content) relative to their nutritional and physiological needs. Therefore, these two AAs must be sufficient in poultry diets. Animal proteins (including ruminant meat & bone meal and hydrolyzed feather meal) are abundant sources of both glycine and proline in chicken nutrition. Clearly, chickens (including broilers and laying hens) have dietary requirements for all proteinogenic AAs to achieve their maximum productivity and maintain optimum health particularly under adverse conditions such as heat stress and disease. This is a paradigm shift in poultry nutrition from the 70-year-old "ideal protein" concept that concerned only about EAAs to the focus of functional AAs that include both EAAs and NEAAs.

Indexed as

Amino AcidsChickensAgedAnimalsDietFemaleHumansNutritional RequirementsNutritional StatusAmino AcidsAmino acidsEgg productionGrowthHealthNutritionProtein

Identifiers

PMID33770405
OpenAlexW3136753548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.