Evidence map›Paper›PMID 33770404›Full record

ArticleAdvances in experimental medicine and biology2021

Amino Acids in Swine Nutrition and Production.

Qian Zhang, Yongqing Hou, Fuller W Bazer, Wenliang He, Erin A Posey, Guoyao Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
31.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  3. Parasites & vectors · 2026
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  4. PreliminaryVeterinary world · 2026
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  11. Article
  12. Article
  13. Article
  14. Characteristics of Nutrition and Metabolism in Dogs and Cats.Advances in experimental medicine and biology · 2024
    Article
  15. Characteristics of the Digestive Tract of Dogs and Cats.Advances in experimental medicine and biology · 2024
    Article
  16. Article
  17. Amino acid nutrition and metabolism in domestic cats and dogs.Journal of animal science and biotechnology · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Qian ZhangHubei International Scientific and Technological Cooperation Base of Animal Nutrition and Gut Health, Wuhan Polytechnic University, Wuhan, China.
Yongqing HouHubei International Scientific and Technological Cooperation Base of Animal Nutrition and Gut Health, Wuhan Polytechnic University, Wuhan, China. houyq@aliyun.com.
Fuller W BazerDepartment of Animal Science, Texas A&M University, College Station, TX, USA.
Wenliang HeDepartment of Animal Science, Texas A&M University, College Station, TX, USA.
Erin A PoseyDepartment of Animal Science, Texas A&M University, College Station, TX, USA.
Guoyao WuDepartment of Animal Science, Texas A&M University, College Station, TX, USA. g-wu@tamu.edu.
Texas A&M University · USWuhan Polytechnic University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amino acids are the building blocks of proteins in animals, including swine. With the development of new analytical methods and biochemical research, there is a growing interest in fundamental and applied studies to reexamine the roles and usage of amino acids (AAs) in swine production. In animal nutrition, AAs have been traditionally classified as nutritionally essential (EAAs) or nutritionally nonessential (NEAAs). AAs that are not synthesized de novo must be provided in diets. However, NEAAs synthesized by cells of animals are more abundant than EAAs in the body, but are not synthesized de novo in sufficient amounts for the maximal productivity or optimal health (including resistance to infectious diseases) of swine. This underscores the conceptual limitations of NEAAs in swine protein nutrition. Notably, the National Research Council (NRC 2012) has recognized both arginine and glutamine as conditionally essential AAs for pigs to improve their growth, development, reproduction, and lactation. Results of recent work have also provided compelling evidence for the nutritional essentiality of glutamate, glycine, and proline for young pigs. The inclusion of so-called NEAAs in diets can help balance AAs in diets, reduce the dietary levels of EAAs, and protect the small intestine from oxidative stress, while enhancing the growth performance, feed efficiency, and health of pigs. Thus, both EAAs and NEAAs are needed in diets to meet the requirements of pigs. This notion represents a new paradigm shift in our understanding of swine protein nutrition and is transforming pork production worldwide.

Indexed as

Amino AcidsAnimal Nutritional Physiological PhenomenaAnimalsDietFemaleLactationNutritional StatusSwineAmino AcidsAmino acidsGrowthHealthMetabolismNutritionSwine

Identifiers

PMID33770404
OpenAlexW3138946620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.