ArticleProtein & cell2021
Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2.
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Article in Protein & cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- A feline coronavirus nucleocapsid protein disrupts ZC3HAV1-viral RNA association to counteract host RNA-level restriction.PLoS pathogens · 2026Article
- Small molecules modulate the biomolecular condensates and liquid‒liquid phase separation.Acta pharmaceutica Sinica. B · 2026Review
- Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase-Separated Co-Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase.Plant biotechnology journal · 2026Article
- Review
- Antiviral drug discovery and development: challenges and future directions.Signal transduction and targeted therapy · 2026Review
- Coronavirus genome packaging and nucleocapsid assembly.Journal of virology · 2026Review
- PARPs and PARP inhibitors: molecular mechanisms and clinical applications.Molecular biomedicine · 2025Review
- The regulatory mechanisms of SARS-CoV-2 N protein helicase and its annealing activity.iScience · 2025Article
- Natural product sennoside B disrupts liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein by inhibiting its RNA-binding activity.Journal of enzyme inhibition and medicinal chemistry · 2025Article
- Dissecting Interactions between RNA and Coronavirus Nucleocapsid Proteins Using Native Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2025Article
- Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding.Communications biology · 2025Article
- Review
- Review
- Purification and Inhibitor Screening of the Full-Length SARS-CoV-2 Nucleocapsid Protein.Molecules (Basel, Switzerland) · 2025Article
- Rational design of phytovirucide inhibiting nucleocapsid protein aggregation in tomato spotted wilt virus.Nature communications · 2025Article
- Regulation of innate immunity by liquid-liquid phase separation: a focus on veterinary viruses.Frontiers in microbiology · 2025Review
- The role of intrinsically disordered regions of SARS-CoV-2 nucleocapsid and non-structural protein 1 proteins.Frontiers in chemistry · 2025Review
- Intrinsic factors behind long COVID: exploring the role of nucleocapsid protein in thrombosis.PeerJ · 2025Review
- Biomolecular condensates and disease pathogenesis.Science China. Life sciences · 2024Review
- SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.Nature communications · 2024Article
Corrections and comments
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Authors and funding
20 authors.
Dan Zhao *Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Weifan Xu *Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Xiaofan Zhang *Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Xiaoting WangSilexon AI Technology Co., Ltd, Nanjing, 210033, China.
Yiyue GeNHC Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China.
Enming YuanInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Yuanpeng XiongBioinformatics Division, BNRIST/Department of Computer Science and Technology, Tsinghua University, Beijing, 100084, China.
Shenyang WuProtein Preparation and Identification Facility, Technology Center for Protein Science, Tsinghua University, Beijing, 100084, China.
Shuya LiInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Nian WuInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Tingzhong TianInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Xiaolong FengInstitute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430074, China.
Hantao ShuInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Peng LangInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Jingxin LiNHC Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China.
Fengcai ZhuNHC Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China.
Xiaokun ShenConvalife (Shanghai) Co., Ltd, Shanghai, 201203, China.
Haitao LiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China.
Pilong LiBeijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, 100084, China. pilongli@mail.tsinghua.edu.cn.
Jianyang ZengInstitute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China. zengjy321@tsinghua.edu.cn.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
COVID-19Nucleocapsid ProteinsCoronavirus Nucleocapsid ProteinsHumansPhosphoproteinsSARS-CoV-2Coronavirus Nucleocapsid ProteinsNucleocapsid ProteinsPhosphoproteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.