Evidence map›Paper›PMID 33770339›Full record

ArticleMolecular neurobiology2021

Dehydroeffusol Pprevents Amyloid β

Haruna Tamano, Mako Takiguchi, Nana Saeki, Misa Katahira, Aoi Shioya, Yukino Tanaka, Mako Egawa, Toshiyuki Fukuda, Hiroki Ikeda, Atsushi Takeda

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Isoproterenol, an adrenergic β receptor agonist, induces metallothionein synthesis followed by canceling amyloid βBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Haruna TamanoDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Mako TakiguchiDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Nana SaekiDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Misa KatahiraDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Aoi ShioyaDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Yukino TanakaDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Mako EgawaDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Toshiyuki FukudaSatoen CO., LTD, 1057 Ohhara, Aoi-ku, Shizuoka, 421-1392, Japan.
Hiroki IkedaSatoen CO., LTD, 1057 Ohhara, Aoi-ku, Shizuoka, 421-1392, Japan.
Atsushi TakedaDepartment of Neurophysiology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. takedaa@u-shizuoka-ken.ac.jp.ORCID http://orcid.org/0000-0001-7519-2957
University of Shizuoka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehydroeffusol, a phenanthrene isolated from Juncus effusus, is a Chinese medicine. To explore an efficacy of dehydroeffusol administration for prevention and cure of Alzheimer's disease, here we examined the effect of dehydroeffusol on amyloid β

Indexed as

Amyloid beta-PeptidesAnimalsDrugs, Chinese HerbalHippocampusHumansInjections, IntraventricularIntracellular FluidMaleNeurodegenerative DiseasesNeuroprotective AgentsPeptide FragmentsPhenanthrenesZincAmyloid beta-Peptidesamyloid beta-protein (1-42)dehydroeffusolDrugs, Chinese HerbalNeuroprotective AgentsPeptide FragmentsPhenanthrenesZincAlzheimer’s diseaseAmyloid β1-42DehydroeffusolJuncus effususMetallothioneinZn2+ dysregulation

Identifiers

PMID33770339
OpenAlexW3136769054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.