ArticleClinical research in cardiology : official journal of the German Cardiac Society2022
Catheter ablation of short-coupled variant of torsade de pointes.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Short-coupled variant of torsade de pointes: A systematic review of case reports and case series.Frontiers in cardiovascular medicine · 2022Pooled it
- Purkinje de-networking for refractory short-coupled premature ventricular contraction-triggered ventricular fibrillation in dextrocardia with situs inversus.HeartRhythm case reports · 2026Article
- Beyond Quinidine: Clinical Lessons From a Child With Short QT Syndrome and Refractory Electrical Storm.JACC. Case reports · 2026Article
- Safety and Efficacy of Intravenous Magnesium for Torsade de Pointes - A Scoping Review.Circulation reports · 2025Review
- Moderator Band and Ventricular Tachycardia: Structural or Functional Substrate?Journal of cardiovascular development and disease · 2023Review
- A case of short-coupled variant of Torsade de Pointes with bystander early repolarization in inferior leads.Journal of cardiology cases · 2023Article
- [Ventricular tachyarrhythmic event: One-lead ECG diagnosis].Herzschrittmachertherapie & Elektrophysiologie · 2023Article
- Comparing the efficacy and safety of medications in adults with hypertrophic cardiomyopathy: a systematic review and network meta-analysis.Frontiers in cardiovascular medicine · 2023Review
- Directed graph mapping shows rotors maintain non-terminating and focal sources maintain self-terminating Torsade de Pointes in canine model.Frontiers in physiology · 2023Article
- [Electrophysiologic study to define the underlying heart rhythm].Herzschrittmachertherapie & Elektrophysiologie · 2022Article
- Pharmacological treatment of short-coupled idiopathic ventricular fibrillation: A review.Indian pacing and electrophysiology journalArticle
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Authors and funding
15 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe short-coupled variant of torsade de pointes (sc-TdP) is a malignant arrhythmia that frequently presents with ventricular fibrillation (VF) electrical storm. Verapamil is considered the first-line therapy of sc-TdP while catheter ablation is not widely adopted. The aim of this study was to determine the origin of sc-TdP and to assess the outcome of catheter ablation using 3D-mapping. METHODS AND
resultsWe retrospectively analyzed five patients with sc-TdP who underwent 3D-mapping and ablation of sc-TdP at five different institutions. Four patients initially presented with sudden cardiac arrest, one patient experienced recurrent syncope as the first manifestation. All patients demonstrated a monomorphic premature ventricular contraction (PVC) with late transition left bundle branch block pattern, superior axis, and a coupling interval of less than 300 ms. triggering recurrent TdP and VF. In four patients, the culprit PVC was mapped to the free wall insertion of the moderator band (MB) with a preceding Purkinje potential in two patients. Catheter ablation using 3D-mapping and intracardiac echocardiography eliminated sc-TdP in all patients, with no recurrence at mean 2.7 years (range 6 months to 8 years) of follow-up.
conclusion3D-mapping and intracardiac echocardiography demonstrate that sc-TdP predominantly originates from the MB free wall insertion and its Purkinje network. Catheter ablation of the culprit PVC at the MB free wall junction leads to excellent short- and long-term results and should be considered as first-line therapy in recurrent sc-TdP or electrical storm.
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