Evidence map›Paper›PMID 33769279›Full record

ArticleeLife2021

Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population.

Jianpeng Sheng, Qi Chen, Xiaoting Wu, Yu Wen Dong, Johannes Mayer, Junlei Zhang, Lin Wang, Xueli Bai, Tingbo Liang, Yang Ho Sung and 3 more

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Monocytes give rise to Langerhans cells that preferentially migrate to lymph nodes at steady state.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. A Non-Coding Oligonucleotide Recruits Cutaneous CD11bAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  6. Article
  7. Macrophage Functions in Psoriasis: Lessons from Mouse Models.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Cross-presenting Langerhans cells are required for the early reactivation of resident CD8Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Jianpeng ShengZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Qi ChenNanyang Technological University, School of Biological Sciences, Singapore, Singapore.ORCID 0000-0002-0658-7629
Xiaoting WuNanyang Technological University, School of Biological Sciences, Singapore, Singapore.ORCID 0000-0002-0281-8717
Yu Wen DongNanyang Technological University, School of Biological Sciences, Singapore, Singapore.
Johannes MayerMalaghan Institute of Medical Research, Wellington, New Zealand.ORCID 0000-0001-6225-7803
Junlei ZhangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lin WangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xueli BaiZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Tingbo LiangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yang Ho SungNanyang Technological University, School of Biological Sciences, Singapore, Singapore.
Wilson Wen Bin GohNanyang Technological University, School of Biological Sciences, Singapore, Singapore.
Franca RoncheseMalaghan Institute of Medical Research, Wellington, New Zealand.
Christiane RuedlNanyang Technological University, School of Biological Sciences, Singapore, Singapore.ORCID 0000-0002-5599-6541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells residing in the skin represent a large family of antigen-presenting cells, ranging from long-lived Langerhans cells (LC) in the epidermis to various distinct classical dendritic cell subsets in the dermis. Through genetic fate mapping analysis and single-cell RNA-sequencing, we have identified a novel separate population of LC-independent CD207

Indexed as

Cell MovementLangerhans CellsAnimalsCell LineageDendritic CellsDermisLymph NodesMiceMice, Inbred C57BLMice, TransgenicSequence Analysis, RNAcell migrationdendritic celldermisimmunologyinflammationLangerhans celllymph nodemouseskin

Identifiers

PMID33769279
PMCPMC8110305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.