Evidence map›Paper›PMID 33769119›Full record

ArticleGlobal spine journal2022

Adult Spinal Deformity Surgery and Frailty: A Systematic Review.

Carl Laverdière, Miltiadis Georgiopoulos, Christopher P Ames, Jason Corban, Pouyan Ahangar, Khaled Awadhi, Michael H Weber

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Combined anterior-posterior versus posterior only approach for surgical management of adult spinal deformity: a systematic review and meta-analysis of comparative studies.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  2. Baseline history of primary fragility fracture is associated with medical complications and revision through 1 year in adult spinal deformity patients undergoing thoracolumbar spinal fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Impact of frailty on surgical outcomes in degenerative cervical myelopathy: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
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  7. Longitudinal comparison of existing frailty indices to predict complications following adult spinal deformity surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  9. Development and validation of a deep learning-powered system for multi-version global alignment and proportion score to predict mechanical complications after adult degenerative scoliosis surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Carl LaverdièreMcGill University Faculty of Medicine, Scoliosis and Spinal Research Unit, Montreal, Quebec, Canada.
Miltiadis GeorgiopoulosMcGill University Faculty of Medicine, Scoliosis and Spinal Research Unit, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0001-8656-1412
Christopher P AmesDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Jason CorbanMcGill University Faculty of Medicine, Scoliosis and Spinal Research Unit, Montreal, Quebec, Canada.
Pouyan AhangarMcGill University Faculty of Medicine, Scoliosis and Spinal Research Unit, Montreal, Quebec, Canada.
Khaled AwadhiMcGill University Faculty of Medicine, Scoliosis and Spinal Research Unit, Montreal, Quebec, Canada.
Michael H WeberMcGill University Faculty of Medicine, Scoliosis and Spinal Research Unit, Montreal, Quebec, Canada.
McGill University · CAUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic review.

objectivesAdult spinal deformity (ASD) can be a debilitating condition with a profound impact on patients' health-related quality of life (HRQoL). Many reports have suggested that the frailty status of a patient can have a significant impact on the outcome of the surgery. The present review aims to identify all pre-operative patient-specific frailty markers that are associated with postoperative outcomes following corrective surgery for ASD of the lumbar and thoracic spine.

methodsA systematic review of the literature was performed to identify findings regarding pre-operative markers of frailty and their association with postoperative outcomes in patients undergoing ASD surgery of the lumbar and thoracic spine. The search was performed in the following databases: PubMed, Embase, Cochrane and CINAHL.

resultsAn association between poorer performance on frailty scales and worse postoperative outcomes. Comorbidity indices were even more frequently employed with similar patterns of association between increased comorbidity burden and postoperative outcomes. Regarding the assessment of HRQoL, worse pre-operative ODI, SF-36, SRS-22 and NRS were shown to be predictors of post-operative complications, while ODI, SF-36 and SRS-22 were found to improve post-operatively.

conclusionsThe findings of this review highlight the true breadth of the concept of "frailty" in ASD surgical correction. These parameters, which include frailty scales and various comorbidity and HRQoL indices, highlight the importance of identifying these factors preoperatively to ensure appropriate patient selection while helping to limit poor postoperative outcomes.

Indexed as

adult spinal deformitycomorbiditydegenerativefrailtyhealth-related quality of lifeHRQoLindexoutcomesspinesurgery

Identifiers

PMID33769119
PMCPMC9109568
OpenAlexW3138561864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.