Evidence map›Paper›PMID 33769023›Full record

ArticleACS applied materials & interfaces2021

Drug-Free Enzyme-Based Bactericidal Nanomotors against Pathogenic Bacteria.

Diana Vilela, Nuria Blanco-Cabra, Ander Eguskiza, Ana C Hortelao, Eduard Torrents, Samuel Sanchez

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. HJournal of nanobiotechnology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Dynamics of Nanomotors Propelled by Enzyme Cascade Reactions.International journal of molecular sciences · 2024
    Article
  10. Review
  11. Ficin-Cyclodextrin-Based Docking Nanoarchitectonics of Self-Propelled Nanomotors for Bacterial Biofilm Eradication.Chemistry of materials : a publication of the American Chemical Society · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Self-Adaptive Flask-like Nanomotors Based on FeNanomaterials (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diana VilelaSmart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.ORCID http://orcid.org/0000-0001-5005-7070
Nuria Blanco-CabraBacterial infections: antimicrobial therapies, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Ander EguskizaSmart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Ana C HortelaoSmart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Eduard TorrentsBacterial infections: antimicrobial therapies, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.ORCID http://orcid.org/0000-0002-3010-1609
Samuel SanchezSmart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.ORCID http://orcid.org/0000-0002-5845-8941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The low efficacy of current conventional treatments for bacterial infections increases mortality rates worldwide. To alleviate this global health problem, we propose drug-free enzyme-based nanomotors for the treatment of bacterial urinary-tract infections. We develop nanomotors consisting of mesoporous silica nanoparticles (MSNPs) that were functionalized with either urease (U-MSNPs), lysozyme (L-MSNPs), or urease and lysozyme (M-MSNPs), and use them against nonpathogenic planktonic

Indexed as

Anti-Bacterial AgentsBiocatalysisBiofilmsCanavaliaDrug CarriersEscherichia coliEscherichia coli InfectionsHumansMuramidaseNanoparticlesSilicon DioxideUreaseUrinary Tract InfectionsAnti-Bacterial AgentsDrug CarriersMuramidaseSilicon DioxideUreasebiofilmsE. colienzymatic nanomotorsinfectionsnanomachinesself-propulsion

Identifiers

PMID33769023
PMCPMC8478280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.