Evidence map›Paper›PMID 33768900›Full record

ArticleClinical case reports2021

Successful treatment of IgG4-related hypertrophic pachymeningitis with induction rituximab and dexamethasone followed by maintenance rituximab.

Karan Seegobin, Muhamad A Moustafa, Nicole Gannon, Katelyn Keller, Jacquelyn Hastings, Vivek Gupta, Han W Tun, Liuyan Jiang

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. IgG4-related spinal hypertrophic pachymeningitis: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Immune Dysregulation in IgGFrontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karan SeegobinDivision of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida Jacksonville FL USA.ORCID https://orcid.org/0000-0002-2739-7357
Muhamad A MoustafaDivision of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida Jacksonville FL USA.ORCID https://orcid.org/0000-0001-8582-1219
Nicole GannonDivision of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida Jacksonville FL USA.
Katelyn KellerDivision of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida Jacksonville FL USA.
Jacquelyn HastingsDivision of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida Jacksonville FL USA.
Vivek GuptaDepartment of Radiology Mayo Clinic Jacksonville Florida Jacksonville FL USA.
Han W TunDivision of Haematology and Medical Oncology Mayo Clinic Jacksonville Florida Jacksonville FL USA.
Liuyan JiangDepartment of Pathology Mayo Clinic Jacksonville Florida Jacksonville FL USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgG4-related disease (IgG4RD) with intracranial involvement is rare. We report a 56-year-old male who had an excellent response to rituximab and dexamethasone after going undiagnosed for 5 years. After 3 years of rituximab maintenance, he has no evidence of disease on brain MRI.

Indexed as

headacheIgG4 diseaselymphoproliferative disordermaintenance rituximabpachymeningitis

Identifiers

PMID33768900
PMCPMC7981770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.