Evidence map›Paper›PMID 33768766›Full record

ArticleRadiology and oncology2021

Multicatheter interstitial brachytherapy versus stereotactic radiotherapy with CyberKnife for accelerated partial breast irradiation: a comparative treatment planning study with respect to dosimetry of organs at risk.

András Herein, Gábor Stelczer, Csilla Pesznyák, Georgina Fröhlich, Viktor Smanykó, Norbert Mészáros, Csaba Polgár, Tibor Major

Open access · goldAbstract readComparative Study
In one paragraph

Article in Radiology and oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The value of brachytherapy in the age of advanced external beam radiotherapy: a review of the literature in terms of dosimetry.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022
    Review
  6. CyberKnife versus multicatheter interstitial brachytherapy for accelerated partial breast irradiation: a dosimetrical assessment with focus on organs at risk.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

András HereinNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Gábor StelczerNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Csilla PesznyákNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Georgina FröhlichNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Viktor SmanykóNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Norbert MészárosNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Csaba PolgárNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
Tibor MajorNational Institute of Oncology, Radiotherapy Centre, Budapest, Hungary.
National Institute of Oncology · HUBudapest University of Technology and Economics · HUEötvös Loránd University · HUSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to dosimetrically compare multicatheter interstitial brachytherapy (MIBT) and stereotactic radiotherapy with CyberKnife (CK) for accelerated partial breast irradiation (APBI) especially concerning the dose of organs at risk (OAR-s). PATIENTS AND

methodsTreatment plans of thirty-two MIBT and CK patients were compared. The OAR-s included ipsilateral non-target and contralateral breast, ipsilateral and contralateral lung, skin, ribs, and heart for left-sided cases. The fractionation was identical (4 x 6.25 Gy) in both treatment groups. The relative volumes (e.g. V100, V90) receiving a given relative dose (100%, 90%), and the relative doses (e.g. D0.1cm

resultsRegarding non-target breast CK performed slightly better than MIBT (V100: 0.7%

conclusionsThe target volume can be properly irradiated by both techniques with similar dose distributions and high dose conformity. Regarding the dose to the non-target breast, heart, and contralateral organs the CK was superior, but the nearby organs (skin, ribs, ipsilateral lung) received less dose with MIBT. The observed dosimetric differences were small but significant in a few parameters at the examined patient number. More studies are needed to explore whether these dosimetric findings have clinical significance.

Indexed as

CathetersBrachytherapyBreastFemaleFiducial MarkersHeartHumansLungOrgans at RiskRadiation DosageRadiation InjuriesRadiometryRibsSkinTumor BurdenUnilateral Breast NeoplasmsAPBICyberKnifedosimetric comparisonmulticatheter interstitial brachytherapy

Identifiers

PMID33768766
PMCPMC8042824
OpenAlexW3139499062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.