Evidence map›Paper›PMID 33768586›Full record

ArticleJournal of clinical pharmacy and therapeutics2021

Methotrexate-associated lymphoproliferative disorder with an osteolytic vertebral lesion in an elderly patient with rheumatoid arthritis: A case report.

Chihiro Hirata, Tsuneaki Kenzaka, Hozuka Akita

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical pharmacy and therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Chihiro HirataDepartment of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tamba, Japan.
Tsuneaki KenzakaDepartment of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tamba, Japan.ORCID https://orcid.org/0000-0002-3120-6605
Hozuka AkitaDepartment of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tamba, Japan.
Tambov State Technical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

WHAT IS KNOWN AND

objectiveMethotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare complication that develops in patients treated with methotrexate (MTX). CASE SUMMARY: A 76-year-old male patient had been taking MTX for his rheumatoid arthritis. Computed tomography (CT) revealed masses in the liver, right adrenal gland and T6-T7 vertebra, including an osteolytic lesion. FDG-PET scan showed increased uptake in each lesion. MTX was discontinued, and CT showed complete remission of the tumours after three months. The disease course confirmed MTX-LPD diagnosis. WHAT IS NEW AND

conclusionBone lesions in LPDs mimic those of metastatic cancer. MTX-LPD should be considered in patients on MTX presenting with mass lesions.

Indexed as

AgedAntirheumatic AgentsArthritis, RheumatoidHumansLymphoproliferative DisordersMaleMethotrexateThoracic VertebraeAntirheumatic AgentsMethotrexateC-reactive proteinelderlylymphoproliferative disordermethotrexaterheumatoid arthritis

Identifiers

PMID33768586
PMCPMC8360114
OpenAlexW3138554316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.