Evidence map›Paper›PMID 33768486›Full record

ArticleProgress in biomaterials2021

Injectable hyaluronic acid-based antibacterial hydrogel adorned with biogenically synthesized AgNPs-decorated multi-walled carbon nanotubes.

Pooyan Makvandi, Milad Ashrafizadeh, Matineh Ghomi, Masoud Najafi, Hamid Heydari Sheikh Hossein, Ali Zarrabi, Virgilio Mattoli, Rajender S Varma

Erratum issuedAbstract read
In one paragraph

Article in Progress in biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Pooyan Makvandi *Istituto Italiano di Tecnologia, Centre for Materials Interface, viale Rinaldo Piaggio 34, 56025, Pontedera, Pisa, Italy. Pooyan.makvandi@iit.it.ORCID http://orcid.org/0000-0003-2456-0961
Milad Ashrafizadeh *Department of Basic Science, Faculty of Veterinary Medicine, University of Tabriz, 51666-16471, Tabriz, Iran.
Matineh Ghomi *Chemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, 61537-53843, Ahvaz, Iran. ma_gh@rocketmail.com.
Masoud NajafiMedical Technology Research Center, Institute of Health Technology, Kermanshah University of Medical Sciences, 6715847141, Kermanshah, Iran. najafi_ma@yahoo.com.
Hamid Heydari Sheikh HosseinDepartment of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.
Ali ZarrabiSabanci University Nanotechnology Research and Application Center (SUNUM), 34956, Tuzla, Istanbul, Turkey.
Virgilio MattoliIstituto Italiano di Tecnologia, Centre for Materials Interface, viale Rinaldo Piaggio 34, 56025, Pontedera, Pisa, Italy.
Rajender S VarmaRegional Centre of Advanced Technologies and Materials, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injectable materials have shown great potential in tissue engineering applications. However, bacterial infection is one of the main challenges in using these materials in the field of regenerative medicine. In this study, biogenically synthesized silver nanoparticle-decorated multi-walled carbon nanotubes (Ag/MWCNTs) were deployed for adorning biogenic-derived AgNPs which were subsequently used in the preparation of thermosensitive hydrogels based on hyaluronic acid encompassing these green-synthesized NPs. The antibacterial capacity of AgNPs decorated on MWCNTs synthesized through Camellia sinensis extract in an organic solvent-free medium displayed a superior activity by inhibiting the growth of Gram-negative (E. coli and Klebsiella) and Gram-positive (S. aureus and E. faecalis). The injectable hydrogel nanocomposites demonstrated good mechanical properties, as well. The thermosensitive hyaluronic acid-based hydrogels also exhibited T

Indexed as

Ag NPsAntibacterialCamellia sinensisGreen synthesisInjectable nanocompositeNanomedicineThermosensitive hydrogels

Identifiers

PMID33768486
PMCPMC8021662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.