Evidence map›Paper›PMID 33768426›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2021

Prospective Study Correlating External Biliary Stenting and Pancreatic Fistula Following Pancreaticoduodenectomy.

Gerardo Blanco-Fernández, Isabel Jaén-Torrejimeno, Noelia De-Armas-Conde, Adela Rojas-Holguín, Jesús Santos Naharro, Juan Manuel Castillo-Tuñón, Diego López-Guerra

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04654299 (Prospective Study Correlating External Biliary Stenting and Pancreatic Fistula Following Pancreaticoduodenectomy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04654299 completednot on this map

Prospective Study Correlating External Biliary Stenting and Pancreatic Fistula Following Pancreaticoduodenectomy

TypeobservationalSponsorUniversidad de ExtremaduraRan2014 to 2018Enrolled128ConditionsPostoperative ComplicationsArmsExternal biliary stent
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gerardo Blanco-FernándezDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain.ORCID 0000-0003-4845-5306
Isabel Jaén-TorrejimenoDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain. isajaent@gmail.com.
Noelia De-Armas-CondeDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain.
Adela Rojas-HolguínDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain.
Jesús Santos NaharroDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain.
Juan Manuel Castillo-TuñónDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain.
Diego López-GuerraDepartment of HBP and Liver Transplant Surgery, University Hospital Complex of Badajoz, University of Extremadura, Avda de Elvas, s/n, 06080, Badajoz, Spain.
Universidad de Extremadura · ESCentro de Implantología Cirugía Oral y Maxilofacial · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pancreatic fistula (POPF) is the most common complication of pancreaticoduodenectomy (PD). Sometimes POPF is associated with biliary fistula (BF) or "mixed" fistula. The purpose of this study is to assess whether the severity of the fistulae, when present, is decreased with an external biliary stent in place.

methodsIn this single-center study, we assessed patients who underwent elective PD from January 2014 to December 2017. Patients were divided into two groups: standard PD (ST-PD) vs. PD with external biliary stent (PD-BS). Demographic, preoperative, intraoperative, and postoperative variables were analyzed, including complications according to the Clavien-Dindo classification, and those specific to pancreatic surgeries, and mortality rates within 90 days of operation.

resultsA total of 128 patients were included (65 in ST-PD group and 63 in PD-BS group). Postoperative complications occurred in 61.7% of patients (32.8%, Clavien-Dindo ≥ III) and were more common among patients in the PD-BS group (44.4% vs. 23.1%; p = 0.03). POPF was also more common among patients in the PD-BS group (39.7% vs. 18.5%; p = 0.008). No statistically significant differences were found for any other complications.

conclusionBased on the results of our study, placement of a transanastomotic external biliary stent does not reduce the rate of pancreatic or biliary fistulae, or their severity; in fact, POPF is more likely when biliary exteriorization is present.

trial registrationNCT04654299.

Indexed as

Pancreatic FistulaPancreaticoduodenectomyHumansPancreaticojejunostomyPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsStentsBiliary stentMorbidityPancreaticoduodenectomyPostoperative pancreatic fistula

Identifiers

PMID33768426
OpenAlexW3136510219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.