Evidence map›Paper›PMID 33768421›Full record

ArticleJournal of autism and developmental disorders2022

Brief Report: Linguistic Mazes and Perseverations in School-Age Boys with Fragile X Syndrome and Autism Spectrum Disorder and Relationships with Maternal Maze Use.

Nell Maltman, Laura Friedman, Emily Lorang, Audra Sterling

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. The impact of individual factors on linguistic alignment of autistic boys and their mothers.Autism : the international journal of research and practice · 2026
    Article
  4. Cognitive-behavioral phenotypes inFrontiers in molecular neuroscience · 2026
    Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nell MaltmanWaisman Center, University of Wisconsin-Madison, Madison, USA. anmaltman@wisc.edu.ORCID http://orcid.org/0000-0001-7874-9925
Laura FriedmanWaisman Center, University of Wisconsin-Madison, Madison, USA.
Emily LorangWaisman Center, University of Wisconsin-Madison, Madison, USA.
Audra SterlingWaisman Center, University of Wisconsin-Madison, Madison, USA.
University of Wisconsin–Madison · US

Funding

POSTDOCTORAL TRAINING IN MENTAL RETARDATION RESEARCHT32HD007489 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Sigan L Hartley · 1995 to 2026
$6.0M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2016 to 2020
$6.0M
Interdisciplinary Training in Speech-Language DisordersT32DC005359 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI ELLIS-WEISMER, SUSAN · 2002 to 2019
$3.7M
The relationship between language and the brain in neurodevelopmental disordersK23DC016639 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI STERLING, AUDRA MARIE · 2018 to 2020
$511k
Grammatical Development in Boys with Fragile X Syndrome and AutismR03DC011616 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI STERLING, AUDRA MARIE · 2011 to 2013
$438k
Eunice Kennedy Shriver National Institute of Child Health and Human Development T32HD007489NICHD NIH HHS T32 HD007489NICHD NIH HHS U54 HD090256NIDCD NIH HHS 1K23DC016639-01NIDCD NIH HHS K23 DC016639NIDCD NIH HHS R03 DC011616NIDCD NIH HHS T32 DC005359
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) and fragile X syndrome (FXS) are neurodevelopmental disorders with overlapping pragmatic language impairments. Prior work suggests pragmatic language differences may run in families. This study examined specific pragmatic difficulties (i.e., linguistic mazes and perseverations) in boys (9-18 years) with idiopathic ASD (n = 26) and FXS+ASD (n = 29), and relationships with maternal maze use. Language samples were obtained separately for boys and mothers. Nonparametric analyses suggested that boys largely did not differ in their rates of mazes, but that boys with FXS+ASD exhibited more perseverations. Mazes were correlated between fragile X dyads. Maternal mazes were correlated with child perseverations among idiopathic ASD dyads. These findings have implications for the etiological significance of ASD-related language phenotypes.

Indexed as

Autism Spectrum DisorderFragile X SyndromeHumansLanguage TestsLinguisticsMaleSchoolsAutism spectrum disorderFragile X syndromeLinguistic mazesParent–child associationsPerseveration

Identifiers

PMID33768421
PMCPMC8463634
OpenAlexW3139200298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.