Evidence map›Paper›PMID 33768405›Full record

ArticleJournal of neuro-oncology2021

Evaluation of Ac-Lys

Bianca M Dijkstra, Marion de Jong, Marcus C M Stroet, Fritz Andreae, Sebastiaan E Dulfer, Marieke Everts, Schelto Kruijff, Julie Nonnekens, Wilfred F A den Dunnen, Frank A E Kruyt and 1 more

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A Cathepsin-Targeted Quenched Activity-Based Probe Facilitates Enhanced Detection of Human Tumors during Resection.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  4. Article
  5. Necrosis binding of Ac-LysEJNMMI research · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Bianca M DijkstraDepartment of Neurosurgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 VB, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-6802-7021
Marion de JongDepartment of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Marcus C M StroetDepartment of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Fritz AndreaepiCHEM Forschungs und EntwicklungsGmbH, Raaba-Grambach, Graz, Austria.
Sebastiaan E DulferDepartment of Neurosurgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 VB, Groningen, The Netherlands.
Marieke EvertsDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Schelto KruijffDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Julie NonnekensDepartment of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Wilfred F A den DunnenDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Frank A E Kruyt *Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-2445-9380
Rob J M Groen *Department of Neurosurgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 VB, Groningen, The Netherlands. r.j.m.groen@umcg.nl.ORCID http://orcid.org/0000-0003-3067-763X
University Medical Center Groningen · NLErasmus MC · NLZentrum für Erinnerungskultur und Geschichtsforschung · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMeningioma recurrence rates can be reduced by optimizing surgical resection with the use of intraoperative molecular fluorescence guided surgery (MFGS). We evaluated the potential of the fluorescent tracer 800CW-TATE for MFGS using in vitro and in vivo models. It targets somatostatin receptor subtype 2 (SSTR

methodsBinding affinity of 800CW-TATE was evaluated using [

results800CW-TATE binding affinity assays showed an IC

conclusion800CW-TATE demonstrated sufficient binding affinity, specific SSTR

Indexed as

Meningeal NeoplasmsMeningiomaAnimalsFluorescenceMicePositron-Emission TomographyTissue Distribution800CW-TATEIntra-operative guidanceMeningiomaMolecular fluorescence guided surgerySomatostatin receptor subtype 2

Identifiers

PMID33768405
PMCPMC8211583
OpenAlexW3137880738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.