Evidence map›Paper›PMID 33768372›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Effects of preoperative nutrition and multimodal prehabilitation on functional capacity and postoperative complications in surgical lung cancer patients: a systematic review.

Vanessa Ferreira, Claire Lawson, Taline Ekmekjian, Francesco Carli, Celena Scheede-Bergdahl, Stéphanie Chevalier

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06716437 (Digitally Enabled Prehabilitation in a Community-based Setting for Patients Undergoing Lung Cancer Surgery), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06716437 narecruitingnot on this mapstarted 2025, after this paper: background citation

Digitally Enabled Prehabilitation in a Community-based Setting for Patients Undergoing Lung Cancer Surgery

TypeinterventionalSponsorUniversity of MelbourneRan2025 to 2025Enrolled25ConditionsLung Cancer (NSCLC)ArmsPrehabilitation
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Guideline
  2. Home-based multimodal prehabilitation before colorectal cancer surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Preoperative prehabilitation in adults: A concept analysis.International journal of nursing studies advances · 2026
    Review
  8. Observational
  9. Article
  10. Article
  11. Testosterone replacement therapy and bladder cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Perspectives on the Direction of Cancer Prehabilitation in the Pandemic and Beyond.Archives of rehabilitation research and clinical translation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vanessa FerreiraDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.
Claire LawsonSchool of Human Nutrition, McGill University, Macdonald-Stewart Building, MS2-043, Macdonald Campus, 21111 Lakeshore Road, Ste-Anne-de-Bellevue, Montreal, QC, H9X 3V9, Canada.
Taline EkmekjianMedical Libraries, McGill University Health Center, Montreal, QC, Canada.
Francesco CarliDepartment of Anesthesia, McGill University Health Centre, Montreal, QC, Canada.
Celena Scheede-BergdahlDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.
Stéphanie ChevalierSchool of Human Nutrition, McGill University, Macdonald-Stewart Building, MS2-043, Macdonald Campus, 21111 Lakeshore Road, Ste-Anne-de-Bellevue, Montreal, QC, H9X 3V9, Canada. stephanie.chevalier@mcgill.ca.ORCID http://orcid.org/0000-0002-8497-1570
McGill University · CAMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effect of preoperative nutrition and multimodal prehabilitation on clinical and functional outcomes in surgical lung cancer patients.

methodsWe searched MEDLINE, Cochrane Library and CENTRAL, EMBASE, Scopus, and clinical trial registries ( clinicaltrials.gov , International Clinical Trials Registry Platform and Google Scholar) to identify studies involving a preoperative nutrition-based intervention or multimodal prehabilitation (nutrition with exercise) of at least 7 days, in lung cancer patients awaiting surgery. Studies must have reported results on at least one of the following outcomes: functional capacity, pulmonary function, postoperative complications, and length of hospital stay. The quality of included studies was assessed using the Cochrane risk of bias assessment tool for randomized trials and the modified Newcastle-Ottawa scale for non-controlled trials.

resultsFive studies were included (1 nutrition-only and 4 multimodal prehabilitation studies). Due to substantial heterogeneity in the interventions across studies, a meta-analysis was not conducted. Findings suggest that multimodal prehabilitation, compared with standard hospital care, is associated with improvements in both functional walking capacity and pulmonary function during the preoperative period; however it does not appear to have an effect on postoperative outcomes. Rather, the finding of significantly lower rates of postoperative complications in the intervention group was unique to the nutrition-only study.

conclusionMultimodal prehabilitation programs that combine nutrition and exercise may have beneficial effects on various physical function outcomes in patients with lung cancer awaiting surgery. Optimizing preoperative nutrition may have postoperative benefits which remain to be confirmed.

Indexed as

Lung NeoplasmsPreoperative ExerciseHumansNutritional StatusPostoperative ComplicationsPreoperative CareNutritional prehabilitationNutrition and exercisePrehabSurgery preparationThoracic surgery

Identifiers

PMID33768372
OpenAlexW3138392334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.