Evidence map›Paper›PMID 33768371›Full record

ReviewCurrent allergy and asthma reports2021

Paget's Disease of Bone: Osteoimmunology and Osteoclast Pathology.

Emily M Rabjohns, Katlyn Hurst, Arin Ghosh, Maria C Cuellar, Rishi R Rampersad, Teresa K Tarrant

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
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  6. Review
  7. Metabolic bone disorders and the promise of marine osteoactive compounds.Cellular and molecular life sciences : CMLS · 2023
    Review
  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Emily M RabjohnsDivision of Rheumatology and Immunology, Department of Medicine, Duke University, DUMC #3874, 200 Trent Dr, Durham, NC, 27710, USA.
Katlyn HurstDuke University, Durham, NC, USA.
Arin GhoshDuke University, Durham, NC, USA.
Maria C CuellarDivision of Rheumatology, Department of Medicine, Hospital del Salvador, Santiago, Chile.
Rishi R RampersadDivision of Rheumatology and Immunology, Department of Medicine, Duke University, DUMC #3874, 200 Trent Dr, Durham, NC, 27710, USA.
Teresa K TarrantDivision of Rheumatology and Immunology, Department of Medicine, Duke University, DUMC #3874, 200 Trent Dr, Durham, NC, 27710, USA. teresa.tarrant@duke.edu.ORCID 0000-0003-4067-5363
Duke University · USHospital del Salvador · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to recognize clinical features of Paget's disease of bone and to describe how the osteoclast, a myeloid-derived cell responsible for bone resorption, contributes to the disease. RECENT

findingsRecent studies have identified several variants in SQSTM1, OPTN, and other genes that may predispose individuals to Paget's disease of bone; studies of these genes and their protein products have elucidated new roles for these proteins in bone physiology. Understanding the pathologic mechanisms in the Pagetic osteoclast may lead to the identification of future treatment targets for other inflammatory and autoimmune diseases characterized by abnormal bone erosion and/or osteoclast activation.

Indexed as

Bone RemodelingOsteitis DeformansOsteoclastsAlgorithmsBone and BonesHumansBisphosphonateChemokine receptorChemokinesOptineurinOsteoclastOsteoimmunologyPaget’s disease of bone

Identifiers

PMID33768371
OpenAlexW3138020855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.