ArticleEuropean radiology2021
Improved detection of in-transit metastases of malignant melanoma with BSREM reconstruction in digital [
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 22 citations in OpenAlex.
- Reduced count pediatric whole-bodyPediatric radiology · 2024Article
- Whole-Body Imaging for the Primary Staging of Melanomas-A Single-Center Retrospective Study.Cancers · 2023Article
- Phantom and clinical evaluation of Block Sequential Regularized Expectation Maximization (BSREM) reconstruction algorithm in 68Ga-PSMA PET-CT studies.Physical and engineering sciences in medicine · 2023Article
- High diagnostic accuracy for lymph node metastasis of oral squamous cell carcinoma using PET/CT with a silicon photomultiplier.Oral radiology · 2022Article
- Small lesion depiction and quantification accuracy of oncologicalEJNMMI physics · 2022Article
- PET/CT variants and pitfalls in malignant melanoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022Review
- The Impact of Total Variation Regularized Expectation Maximization Reconstruction onFrontiers in medicine · 2022Article
- Predictive Value of Baseline [18F]FDG PET/CT for Response to Systemic Therapy in Patients with Advanced Melanoma.Journal of clinical medicine · 2021Article
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Authors and funding
15 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare block sequential regularized expectation maximization (BSREM) and ordered subset expectation maximization (OSEM) for the detection of in-transit metastasis (ITM) of malignant melanoma in digital [
methodsWe retrospectively analyzed a cohort of 100 [
resultsBSREM reconstruction led to the detection of 287 ITM (39% more than OSEM). PET parameters of ITM were significantly different between BSREM and OSEM reconstructions (p < 0.001). SUVmax and TBR were higher (76.5% and 77.7%, respectively) and MTV lower (49.5%) on BSREM. ITM missed with OSEM had significantly lower SUVmax (mean 2.03 vs. 3.84) and TBR (mean 1.18 vs. 2.22) and higher MTV (mean 2.92 vs. 1.01) on OSEM compared to BSREM (all p < 0.001).
conclusionsBSREM detects significantly more ITM than OSEM, owing to higher SUVmax, higher TBR, and less blurring. BSREM is particularly helpful in small and less avid lesions, which are more often missed with OSEM. KEY POINTS: • In melanoma patients, [
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