Evidence map›Paper›PMID 33767914›Full record

ArticleMolecular therapy. Nucleic acids2021

The lncRNAs

Iris Eke, Michelle A Bylicky, Veit Sandfort, Sunita Chopra, Shannon Martello, Edward E Graves, C Norman Coleman, Molykutty J Aryankalayil

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Nucleic acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Emerging evidence for adapting radiotherapy to immunotherapy.Nature reviews. Clinical oncology · 2023
    Review
  11. Prostate cancer in omics era.Cancer cell international · 2022
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. The Emerging Roles of LINC00665 in Human Cancers.Frontiers in cell and developmental biology · 2022
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Iris EkeDepartment of Radiation Oncology, Stanford University School of Medicine, Center for Clinical Sciences Research (CCSR), Stanford, CA 94305, USA.
Michelle A BylickyRadiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Veit SandfortDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sunita ChopraRadiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Shannon MartelloRadiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Edward E GravesDepartment of Radiation Oncology, Stanford University School of Medicine, Center for Clinical Sciences Research (CCSR), Stanford, CA 94305, USA.
C Norman ColemanRadiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Molykutty J AryankalayilRadiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
National Institutes of Health · USStanford University · US

Funding

Radiation-induced molecular targetsZIABC010670 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI COLEMAN, NORMAN · 2009 to 2024
$17.3M
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been shown to impact important biological functions such as proliferation, survival, and genomic stability. To analyze radiation-induced lncRNA expression in human tumors, we irradiated prostate cancer cells with a single dose of 10 Gy or a multifractionated radiotherapeutic regimen of 10 fractions with a dose of 1 Gy (10 × 1 Gy) during 5 days. We found a stable upregulation of the lncRNA

Indexed as

3D cell cultureDNA repairfractionated radiationlong non-coding RNAmicro RNAprostate cancerradiation-induced targetsradiation stress responsetargeted therapytumor adaptation

Identifiers

PMID33767914
PMCPMC7960506
OpenAlexW3131258124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.