Evidence map›Paper›PMID 33767724›Full record

ArticleFrontiers in plant science2021

Exploring microRNA Signatures of DNA Damage Response Using an Innovative System of Genotoxic Stress in

Carla Gualtieri, Maraeva Gianella, Andrea Pagano, Tiziano Cadeddu, Susana Araújo, Alma Balestrazzi, Anca Macovei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  3. Genes · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Carla GualtieriPlant Biotechnology Laboratory, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Maraeva GianellaPlant Biotechnology Laboratory, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Andrea PaganoPlant Biotechnology Laboratory, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Tiziano CadedduPlant Biotechnology Laboratory, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Susana AraújoInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Alma BalestrazziPlant Biotechnology Laboratory, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Anca MacoveiPlant Biotechnology Laboratory, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
University of Pavia · ITHospital Center of Cova da Beira · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the challenges that living organisms face is to promptly respond to genotoxic stress to avoid DNA damage. To this purpose, all organisms, including plants, developed complex DNA damage response (DDR) mechanisms. These mechanisms are highly conserved among organisms and need to be finely regulated. In this scenario, microRNAs (miRNAs) are emerging as active players, thus attracting the attention of the research community. The involvement of miRNAs in DDR has been investigated prominently in human cells whereas studies in plants are still scarce. To experimentally investigate the involvement of plant miRNAs in the regulation of DDR-associated pathways, an

Indexed as

camptothecinDNA damage responsegenotoxicitymicroRNANSC120686seedling developmenttyrosyl-DNA phosphodiesterase 1

Identifiers

PMID33767724
PMCPMC7985446
OpenAlexW3135762095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.