ArticleFrontiers in immunology2021
PD-1 Blockade Modulates Functional Activities of Exhausted-Like T Cell in Patients With Cutaneous Leishmaniasis.
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In one paragraph
Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 35 citations in OpenAlex.
- Cytotoxic CD4Parasite immunology · 2026Article
- Characterization of the activation status of T lymphocyte subpopulations in peripheral blood from localized and diffused cutaneous leishmaniasis patients at the University of Gondar Hospital, Ethiopia.BMC infectious diseases · 2026Article
- Revisiting the past in light of current knowledge on γδ T cells in leishmaniasis.Frontiers in immunology · 2026Review
- Cutaneous and Mucocutaneous Leishmaniasis: Perspectives on Immunity, Virulence, and Treatment.Biomedicines · 2025Review
- Leishmania amazonensis infection induces PD-L1 expression on dendritic cells and impairs Th1 responses in vitro and in vivo.Scientific reports · 2025Article
- Review
- PIAS1 Shapes a Tumor-Suppressive Microenvironment by Suppressing Immune Evasion in Oral Squamous Cell Carcinoma.Cancers · 2025Article
- Impact of co-infection with Plasmodium berghei ANKA in Leishmania major-parasitized mice on immune modulation and cutaneous leishmaniasis.PLoS neglected tropical diseases · 2025Article
- IL-32-producing CD8+ memory T cells define immunoregulatory niches in human cutaneous leishmaniasis.The Journal of clinical investigation · 2025Article
- T-cell and Soluble Co-inhibitory Receptor Expression in Patients With Visceral Leishmaniasis Are Markers of Treatment Response and Clinical Outcome.Open forum infectious diseases · 2024Article
- High PD-1 and CTLA-4 expression correlates with host immune suppression in patients and a mouse model infected with Echinococcus multilocularis.Parasites & vectors · 2024Article
- NKG2C+CD57+ natural killer cells with senescent features are induced during cutaneous leishmaniasis and accumulate in patients with lesional healing impairment.Clinical and experimental immunology · 2024Article
- The Parasitemia has Contributed to the Severity of Cases of Visceral Leishmaniasis.Indian journal of microbiology · 2024Article
- Senescent T cells: Beneficial and detrimental roles.Immunological reviews · 2023Review
- A Comprehensive Pan-Cancer Analysis Identifies CEP55 as a Potential Oncogene and Novel Therapeutic Target.Diagnostics (Basel, Switzerland) · 2023Article
- Immunosenescence and Skin: A State of Art of Its Etiopathogenetic Role and Crucial Watershed for Systemic Implications.International journal of molecular sciences · 2023Review
- Taurine enhances the antitumor efficacy of PD-1 antibody by boosting CD8Cancer immunology, immunotherapy : CII · 2023Article
- CXCR5 and TIM-3 expressions define distinct exhausted T cell subsets in experimental cutaneous infection withFrontiers in immunology · 2023Article
- Development of Ag-ZnO/AgO Nanocomposites Effectives forPharmaceutics · 2022Article
- Ageing impairs protective immunity and promotes susceptibility to murine visceral leishmaniasis.Parasitology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 6 institutions in 3 countries.
Renan Garcia de MouraNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Luciana Polaco CovreNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Carlos Henrique FantecelleNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Vitor Alejandro Torres GajardoNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Carla Baroni CunhaNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Lorenzzo Lyrio StringariNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Ashton Trey BelewDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, United States.
Camila Batista DanielNúcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Sandra Ventorin Von ZeidlerNúcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Carlos Eduardo TadokoroUniversidade Vila Velha, Vila Velha, Brazil.
Herbert Leonel de Matos GuedesInstituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Raphael Lubiana ZanottiSecretaria Estadual de Saúde do Espírito Santo-SESA, Vitoria, Brazil.
David MosserDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, United States.
Aloisio FalquetoDepartamento de Medicina Social, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Arne N AkbarDivision of Medicine, University College London, London, United Kingdom.
Daniel Claudio Oliveira GomesNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Universidade Federal do Espírito Santo · BRUniversity College London · GBUniversity of Maryland, College Park · USSecretaria da Saúde · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Vila Velha · BR
Funding
Medical Research Council MR/T015853/1
Abstract
Patients infected by
Indexed as
AdultCell ProliferationFemaleHumansImmune Checkpoint InhibitorsImmune Checkpoint ProteinsImmunosenescenceInflammationInterferon-gammaLeishmania braziliensisLeishmaniasis, CutaneousMaleMiddle AgedProgrammed Cell Death 1 ReceptorSkinT-LymphocytesIFNG protein, humanImmune Checkpoint InhibitorsImmune Checkpoint ProteinsInterferon-gammaPDCD1 protein, humanProgrammed Cell Death 1 Receptorcutaneous leishmaniasisimmunosenescenceinhibitory checkpoint receptorsLeishmania braziliensisPD-1senescent T cellsT cell exhaustion
Identifiers
What OpenQuestion holds
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LicenceCC BY
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Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.