Evidence map›Paper›PMID 33767594›Full record

ArticleInternational journal of biological sciences2021

PTEN-mediated AKT/β-catenin signaling enhances the proliferation and expansion of Lgr5+ hepatocytes.

Jimin Han, Kaijun Lin, Xuezheng Zhang, Lingchen Yan, Yu Chen, Haiyan Chen, Jianjun Liu, Jia Liu, Yaojiong Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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  10. Immune Cytolytic Activity and Strategies for Therapeutic Treatment.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jimin HanSchool of Life Sciences, Tsinghua University, China.
Kaijun LinSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, China.
Xuezheng ZhangSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, China.
Lingchen YanSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, China.
Yu ChenSchool of Life Sciences, Tsinghua University, China.
Haiyan ChenSchool of Life Sciences, Tsinghua University, China.
Jianjun LiuMedical Key Laboratory of Health Toxicology of Shenzhen, Shenzhen Center for Disease Control and Prevention, 518054, Shenzhen, China.
Jia LiuSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, China.
Yaojiong WuSchool of Life Sciences, Tsinghua University, China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Liver RegenerationAnimalsbeta CateninHepatocytesMice, TransgenicProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseReceptors, G-Protein-Coupledbeta CateninLgr5 protein, mouseProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePten protein, mouseReceptors, G-Protein-CoupledAKT/β-cateninhepatocyteLgr5liver regeneration.proliferation

Identifiers

PMID33767594
PMCPMC7975694
OpenAlexW3130579659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.