ArticleScientific reports2021
Long-term changes in the small-world organization of brain networks after concussion.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using neuroimaging to identify sex differences in adults with sports-related concussion: a systematic review.Brain imaging and behavior · 2025Pooled it
- Dual-task testing in adults with persistent postconcussive symptoms: a scoping review with conceptual mapping approach.Experimental brain research · 2026Article
- Establishing the link between post-concussive symptoms and brain network dysfunction: A systematic scoping review of neuroimaging evidence.NeuroImage. Clinical · 2026Article
- Linking a Deep Learning Model for Concussion Classification with Reorganization of Large-Scale Brain Networks in Female Youth.Bioengineering (Basel, Switzerland) · 2025Article
- Self-reported concussion history is not related to cortical volume in college athletes.PloS one · 2025Article
- Regression-Based Classification of the Middle-Latency Auditory-Evoked Potentials in Vestibular Migraine and Concussion Patients with Dizziness.Brain sciences · 2024Article
- Impact of moderate aerobic exercise on small-world topology and characteristics of brain networks after sport-related concussion: an exploratory study.Scientific reports · 2024Article
- Differential neural mechanisms for movement adaptations following neuromuscular training in young female athletes with a history of sports-related concussion.Neuroscience · 2024Article
- Rethinking recovery in adolescent concussions: Network-level functional connectivity alterations associated with motor deficits.Human brain mapping · 2023Article
- Mild traumatic brain injury history is associated with lower brain network resilience in soldiers.Brain communications · 2023Article
- Altered Default Mode Network Functional Connectivity in Parkinson's Disease: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2022Article
- Disrupted topological organization of the motor execution network in Wilson's disease.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
There is a growing body of literature using functional MRI to study the acute and long-term effects of concussion on functional brain networks. To date, studies have largely focused on changes in pairwise connectivity strength between brain regions. Less is known about how concussion affects whole-brain network topology, particularly the "small-world" organization which facilitates efficient communication at both local and global scales. The present study addressed this knowledge gap by measuring local and global efficiency of 26 concussed athletes at acute injury, return to play (RTP) and one year post-RTP, along with a cohort of 167 athletic controls. On average, concussed athletes showed no alterations in local efficiency but had elevated global efficiency at acute injury, which had resolved by RTP. Athletes with atypically long recovery, however, had reduced global efficiency at 1 year post-RTP, suggesting long-term functional abnormalities for this subgroup. Analyses of nodal efficiency further indicated that global network changes were driven by high-efficiency visual and sensorimotor regions and low-efficiency frontal and subcortical regions. This study provides evidence that concussion causes subtle acute and long-term changes in the small-world organization of the brain, with effects that are related to the clinical profile of recovery.
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