ArticleScientific reports2021
Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Mild SARS-CoV-2 maternal infection in mice induces transient offspring neurodevelopmental aberrance.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Mortality, intensive care unit admission, and ventilatory support in pregnant and nonpregnant women with COVID-19 in Brazil: a paired observational study.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Observational
- Article
- Courage in Decision Making: A Mixed-Methods Study of COVID-19 Vaccine Uptake in Women of Reproductive Age in the U.K.Vaccines · 2024Article
- Characteristics and Outcomes of Coronavirus Disease- 2019 Among Pregnant Women in Saudi Arabia; a Retrospective Study.International journal of women's health · 2024Article
- A COVID Dilemma: How to Manage Pregnancies in Case of Severe Respiratory Failure?Healthcare (Basel, Switzerland) · 2023Article
- Clinical Outcomes of COVID-19 Infection in Pregnant and Nonpregnant Women: Results from The Philippine CORONA Study.Vaccines · 2023Article
- Adaptation and psychometric study of the scale for the measurement of fear and anxiety of COVID-19 disease in pregnant women (AMICO_Pregnant).Frontiers in public health · 2023Article
- Antepartum SARS-CoV-2 infection and adverse birth outcomes in South African women.Journal of global health · 2022Article
- Social determinants of health associated with COVID-19 severity during pregnancy: a multinational cohort study (in the International Registry of Coronavirus Exposure in Pregnancy).BMC public health · 2022Observational
- Integrating in silico and in vivo approach for investigating the role of polyherbal oil in prevention and treatment of COVID-19 infection.Chemico-biological interactions · 2022Article
- Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review.Journal of clinical medicine · 2022Review
- COVID-19 disease and vaccination in pregnant and lactating women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022Review
- COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study.Scientific reports · 2022Observational
- What to Expect from COVID-19 and from COVID-19 Vaccine for Expecting or Lactating Women.Pediatric reports · 2022Review
- SARS-CoV-2 infection and COVID-19 vaccination in pregnancy.Nature reviews. Immunology · 2022Review
- Birthing parents had a lower risk of testing positive for SARS-CoV-2 in the peripartum period in Norway, 15Infection prevention in practice · 2021Article
- Interleukin-37: A Link Between COVID-19, Diabetes, and the Black Fungus.Frontiers in microbiology · 2021Review
- Article
Corrections and comments
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Authors and funding
18 authors at 6 institutions in 3 countries.
Funding
Abstract
We tested whether pregnant and non-pregnant women differ in COVID-19 symptom profile and severity, and we extended previous investigations on hospitalized pregnant women to those who did not require hospitalization. Two female community-based cohorts (18-44 years) provided longitudinal (smartphone application, N = 1,170,315, n = 79 pregnant tested positive) and cross-sectional (web-based survey, N = 1,344,966, n = 134 pregnant tested positive) data, prospectively collected through self-participatory citizen surveillance in UK, Sweden and USA. Pregnant and non-pregnant were compared for frequencies of events, including SARS-CoV-2 testing, symptoms and hospitalization rates. Multivariable regression was used to investigate symptoms severity and comorbidity effects. Pregnant and non-pregnant women positive for SARS-CoV-2 infection were not different in syndromic severity, except for gastrointestinal symptoms. Pregnant were more likely to have received testing, despite reporting fewer symptoms. Pre-existing lung disease was most closely associated with syndromic severity in pregnant hospitalized. Heart and kidney diseases and diabetes increased risk. The most frequent symptoms among non-hospitalized women were anosmia [63% pregnant, 92% non-pregnant] and headache [72%, 62%]. Cardiopulmonary symptoms, including persistent cough [80%] and chest pain [73%], were more frequent among pregnant who were hospitalized. Consistent with observations in non-pregnant populations, lung disease and diabetes were associated with increased risk of more severe SARS-CoV-2 infection during pregnancy.
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