Evidence map›Paper›PMID 33767274›Full record

ArticleScientific reports2021

Toxicity of the insecticide sulfoxaflor alone and in combination with the fungicide fluxapyroxad in three bee species.

C Azpiazu, J Bosch, L Bortolotti, P Medrzycki, D Teper, R Molowny-Horas, F Sgolastra

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 80 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

C AzpiazuDipartimento di Scienze e Tecnologie Agro-Alimentari, Alma Mater Studiorum Università di Bologna, Viale Fanin 42, 40127, Bologna, Italy.
J BoschCREAF, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
L BortolottiCREA-Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia Agraria, Centro di Ricerca Agricoltura ed Ambiente, Via Corticella 133, 40128, Bologna, Italy.
P MedrzyckiCREA-Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia Agraria, Centro di Ricerca Agricoltura ed Ambiente, Via Corticella 133, 40128, Bologna, Italy.
D TeperApiculture Division, Research Institute of Horticulture, 2A Kazmierska St., 24100, Puławy, Poland.
R Molowny-HorasCREAF, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
F SgolastraDipartimento di Scienze e Tecnologie Agro-Alimentari, Alma Mater Studiorum Università di Bologna, Viale Fanin 42, 40127, Bologna, Italy. fabio.sgolastra2@unibo.it.
Universitat Autònoma de Barcelona · ESUniversity of Bologna · ITCentro Agricoltura Ambiente (Italy) · ITConsiglio per la ricerca in agricoltura e l’analisi dell’economia agraria · ITInstytut Ogrodnictwa · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sulfoximine insecticide sulfoxaflor is regarded as a potential substitute for neonicotinoids that were recently banned in the EU due to their side effects on bees. Like neonicotinoids, sulfoxaflor acts as a competitive modulator of nicotinic acetylcholine receptors. In agricultural environments, bees are commonly exposed to combinations of pesticides, and neonicotinoids are known to interact synergistically with fungicides. The objective of our study is to assess the acute oral toxicity of sulfoxaflor alone and in combination with a single dose of fluxapyroxad, a succinate dehydrogenase inhibitor (SDHI) fungicide, in three bee species: Apis mellifera, Bombus terrestris and Osmia bicornis. Because synergism may be dose-dependent, we tested a range of sulfoxaflor doses. Synergistic effects were assessed using three different approaches: Bliss criterion of drugs independence, ratio test comparing LD

Indexed as

AmidesAnimalsBeesDrug SynergismEnvironmental MonitoringFungicides, IndustrialInsecticidesLethal Dose 50PyridinesSulfur CompoundsAmidesfluxapyroxadFungicides, IndustrialInsecticidesPyridinessulfoxaflorSulfur Compounds

Identifiers

PMID33767274
PMCPMC7994444
OpenAlexW3138182073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.