ArticleScientific reports2021
Successful extraction of insect DNA from recent copal inclusions: limits and perspectives.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Resin does not safeguard insect DNA during early decay despite preservation of soft tissues.Scientific reports · 2026Article
- Archaeoentomological SedaDNA from two French gallo-roman wells reveals the presence of arthropods not identified by sclerotized remains.Scientific reports · 2026Article
- Morphology of male genitalia, legs, and wing venation reveals the classification of Mesozoic Zoraptera (Insecta).Frontiers in zoology · 2026Article
- Non-destructive DNA extraction for recovering mitochondrial genomes from museum grasshopper specimens.PloS one · 2026Article
- Novel Sources of Biodiversity and Biomolecules from Bacteria Isolated from a High Middle Ages Soil Sample in Palermo (Sicily, Italy).Microbiology spectrum · 2023Article
- Morphological and organic spectroscopic studies of a 44-million-year-old leaf beetle (Coleoptera: Chrysomelidae) in amber with endogenous remains of chitin.Scientific reports · 2023Article
- The significance of cephalopod beaks as a research tool: An update.Frontiers in physiology · 2022Review
- Rapid and zero-cost DNA extraction from soft-bodied insects for routine PCR-based applications.PloS one · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insects entombed in copal, the sub-fossilized resin precursor of amber, represent a potential source of genetic data for extinct and extant, but endangered or elusive, species. Despite several studies demonstrated that it is not possible to recover endogenous DNA from insect inclusions, the preservation of biomolecules in fossilized resins samples is still under debate. In this study, we tested the possibility of obtaining endogenous ancient DNA (aDNA) molecules from insects preserved in copal, applying experimental protocols specifically designed for aDNA recovery. We were able to extract endogenous DNA molecules from one of the two samples analyzed, and to identify the taxonomic status of the specimen. Even if the sample was found well protected from external contaminants, the recovered DNA was low concentrated and extremely degraded, compared to the sample age. We conclude that it is possible to obtain genomic data from resin-entombed organisms, although we discourage aDNA analysis because of the destructive method of extraction protocols and the non-reproducibility of the results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.