Evidence map›Paper›PMID 33767208›Full record

Trial reportScientific reports2021

Comprehensive verbal fluency features predict executive function performance.

Julia Amunts, Julia A Camilleri, Simon B Eickhoff, Kaustubh R Patil, Stefan Heim, Georg G von Polier, Susanne Weis

Abstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Screening for Executive Impairment in Patients with Frontotemporal Dementia: Evidence from the Greek Version of the Frontier Executive Screen.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
  16. Normative Data for the Famous People Fluency Test in the Adult French-Quebec Population and Validation Study in Mild Cognitive Impairment and Alzheimer's Disease.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia AmuntsInstitute of Neuroscience and Medicine (INM-7 Brain and Behaviour), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany. j.amunts@fz-juelich.de.
Julia A CamilleriInstitute of Neuroscience and Medicine (INM-7 Brain and Behaviour), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany.
Simon B EickhoffInstitute of Neuroscience and Medicine (INM-7 Brain and Behaviour), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany.
Kaustubh R PatilInstitute of Neuroscience and Medicine (INM-7 Brain and Behaviour), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany.
Stefan HeimInstitute of Neuroscience and Medicine (INM-1 Structural and functional organization of the brain), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany.
Georg G von PolierInstitute of Neuroscience and Medicine (INM-7 Brain and Behaviour), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany.
Susanne WeisInstitute of Neuroscience and Medicine (INM-7 Brain and Behaviour), Forschungszentrum Jülich, Wilhelm-Johnen-Str, 52428, Jülich, Germany.

Funding

Meta-anaylsis in human brain mappingR01MH074457 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FOX, PETER THORNTON · 2006 to 2024
$10.5M
Meta-analysis in human brain mappingR56MH074457 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FOX, PETER THORNTON · 2020 to 2020
$543k
NIMH NIH HHS R01 MH074457NIMH NIH HHS R56 MH074457
6 · The paper itself

Abstract

Semantic verbal fluency (sVF) tasks are commonly used in clinical diagnostic batteries as well as in a research context. When performing sVF tasks to assess executive functions (EFs) the sum of correctly produced words is the main measure. Although previous research indicates potentially better insights into EF performance by the use of finer grained sVF information, this has not yet been objectively evaluated. To investigate the potential of employing a finer grained sVF feature set to predict EF performance, healthy monolingual German speaking participants (n = 230) were tested with a comprehensive EF test battery and sVF tasks, from which features including sum scores, error types, speech breaks and semantic relatedness were extracted. A machine learning method was applied to predict EF scores from sVF features in previously unseen subjects. To investigate the predictive power of the advanced sVF feature set, we compared it to the commonly used sum score analysis. Results revealed that 8 / 14 EF tests were predicted significantly using the comprehensive sVF feature set, which outperformed sum scores particularly in predicting cognitive flexibility and inhibitory processes. These findings highlight the predictive potential of a comprehensive evaluation of sVF tasks which might be used as diagnostic screening of EFs.

Indexed as

Executive FunctionVerbal BehaviorAdultFemaleHealthy VolunteersHumansMachine LearningMaleMiddle AgedSemanticsYoung Adult

Identifiers

PMID33767208
PMCPMC7994566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.