Evidence map›Paper›PMID 33767203›Full record

ArticleScientific data2021

NLM-Chem, a new resource for chemical entity recognition in PubMed full text literature.

Rezarta Islamaj, Robert Leaman, Sun Kim, Dongseop Kwon, Chih-Hsuan Wei, Donald C Comeau, Yifan Peng, David Cissel, Cathleen Coss, Carol Fisher and 9 more

Abstract read
In one paragraph

Article in Scientific data, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  12. Towards discovery: an end-to-end system for uncovering novel biomedical relations.Database : the journal of biological databases and curation · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Semantics-enabled biomedical literature analytics.Journal of biomedical informatics · 2024
    Article
  17. A Comprehensive Evaluation of Biomedical Entity Linking Models.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Rezarta Islamaj *National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.ORCID 0000-0001-5651-1860
Robert Leaman *National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.ORCID 0000-0003-3296-5766
Sun KimNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.ORCID 0000-0003-3072-6649
Dongseop KwonNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Chih-Hsuan WeiNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Donald C ComeauNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.ORCID 0000-0002-9373-530X
Yifan PengNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.ORCID 0000-0001-9309-8331
David CisselNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Cathleen CossNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Carol FisherNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Rob GuzmanNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Preeti Gokal KocharNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.ORCID 0000-0003-2109-1100
Stella KoppelNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Dorothy TrinhNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Keiko SekiyaNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Janice WardNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Deborah WhitmanNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Susan SchmidtNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Zhiyong LuNational Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA. Zhiyong.Lu@nih.gov.

Funding

National Biomedical Information ServicesZIHLM200888 · NLM · NATIONAL LIBRARY OF MEDICINE · PI PALTOO, DINA · 2009 to 2025
$5200.7M
Query Log Analysis for Improving User Access to NCBI Web ServicesZIALM000001 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2011 to 2021
$12.8M
A framework to enhance radiology structured report by invoking NLP and DL: Models and ApplicationsR00LM013001 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI PENG, YIFAN · 2020 to 2022
$710k
NLM NIH HHS R00 LM013001U.S. Department of Health & Human Services | NIH | U.S. National Library of Medicine (NLM) Intramural Research Program
6 · The paper itself

Abstract

Automatically identifying chemical and drug names in scientific publications advances information access for this important class of entities in a variety of biomedical disciplines by enabling improved retrieval and linkage to related concepts. While current methods for tagging chemical entities were developed for the article title and abstract, their performance in the full article text is substantially lower. However, the full text frequently contains more detailed chemical information, such as the properties of chemical compounds, their biological effects and interactions with diseases, genes and other chemicals. We therefore present the NLM-Chem corpus, a full-text resource to support the development and evaluation of automated chemical entity taggers. The NLM-Chem corpus consists of 150 full-text articles, doubly annotated by ten expert NLM indexers, with ~5000 unique chemical name annotations, mapped to ~2000 MeSH identifiers. We also describe a substantially improved chemical entity tagger, with automated annotations for all of PubMed and PMC freely accessible through the PubTator web-based interface and API. The NLM-Chem corpus is freely available.

Indexed as

SoftwareTerminology as TopicData MiningOrganic ChemicalsPharmaceutical PreparationsPubMedOrganic ChemicalsPharmaceutical Preparations

Identifiers

PMID33767203
PMCPMC7994842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.