Evidence map›Paper›PMID 33766917›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Ivan J Santiago, Dawei Zhang, Arunesh Saras, Nicholas Pontillo, Chundi Xu, Xiaoting Chen, Matthew T Weirauch, Meeta Mistry, David D Ginty, Matthew Y Pecot and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

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  10. Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ivan J SantiagoDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Dawei ZhangDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Arunesh SarasDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Nicholas PontilloDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Chundi XuDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-1056-8893
Xiaoting ChenCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
Matthew T WeirauchCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
Meeta MistryDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115.ORCID 0000-0002-5830-9479
David D GintyHHMI, Harvard Medical School, Boston, MA 02115 david_ginty@hms.harvard.edu Jing_Peng@hms.harvard.edu.
Matthew Y PecotDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Jing PengDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115; david_ginty@hms.harvard.edu Jing_Peng@hms.harvard.edu.ORCID 0000-0003-2762-7148
Harvard University · USCincinnati Children's Hospital Medical Center · US

Funding

Binding of Epstein Barr Virus EBNA2 Unifies Multiple Sclerosis Genetic MechanismsR01NS099068 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI Leah Claire Kottyan, Matthew Tyson Weirauch · 2017 to 2026
$4.2M
Circuit-specific transcriptional mechanisms underlying the precision of synaptic connectivityR01NS103905 · NINDS · HARVARD MEDICAL SCHOOL · PI GINTY, DAVID D · 2019 to 2020
$732k
NINDS NIH HHS R01 NS099068NINDS NIH HHS R01 NS103905
6 · The paper itself

Abstract

The layered compartmentalization of synaptic connections, a common feature of nervous systems, underlies proper connectivity between neurons and enables parallel processing of neural information. However, the stepwise development of layered neuronal connections is not well understood. The medulla neuropil of the

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsDrosophila melanogasterDrosophila ProteinsNeuronsPoint MutationRepressor ProteinsSynapsesTranscription FactorsVisual PathwaysDrosophila Proteinserm protein, DrosophilaRepressor Proteinsslp1 protein, DrosophilaTranscription FactorsdFezfgrowth conelaminar organizationneural connectivitytranscription

Identifiers

PMID33766917
PMCPMC8020669
OpenAlexW3137584932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.