Evidence map›Paper›PMID 33766904›Full record

ArticleMicrobiology resource announcements2021

Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.

Daniel W Renner, Lance Parsons, Jacob T Shreve, Esteban A Engel, Chad V Kuny, Lynn Enquist, Donna Neumann, Colleen Mangold, Moriah L Szpara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology resource announcements, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel W RennerDepartment of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
Lance ParsonsLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.
Jacob T ShreveDepartment of Biochemistry and Molecular Biology, Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
Esteban A EngelPrinceton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA.
Chad V KunyDepartment of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
Lynn EnquistDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Donna NeumannDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Colleen MangoldDepartment of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
Moriah L SzparaDepartment of Biology, Pennsylvania State University, University Park, Pennsylvania, USA moriah@psu.edu.ORCID https://orcid.org/0000-0001-9859-1678

Funding

Forward genetic prediction and testing of virulence loci in herpes simplex virus 1R01AI132692 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI SZPARA, MORIAH · 2018 to 2022
$2.3M
NIAID NIH HHS R01 AI132692
6 · The paper itself

Abstract

Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.

Identifiers

PMID33766904
PMCPMC7996463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.