Evidence map›Paper›PMID 33765941›Full record

ArticleBMC infectious diseases2021

'Long COVID': persistent COVID-19 symptoms in survivors managed in Lagos State, Nigeria.

Bodunrin Osikomaiya, Olufemi Erinoso, Kikelomo Ololade Wright, Aina Olufemi Odusola, Babafemi Thomas, Oluwatosin Adeyemi, Abimbola Bowale, Olusola Adejumo, Ayodeji Falana, Ismail Abdus-Salam and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Bodunrin OsikomaiyaLagos Blood Transfusion Services, Lagos, Nigeria.
Olufemi ErinosoLagos State University Teaching Hospital, Lagos, Lagos State, Nigeria. Olufemierinoso@gmail.com.ORCID http://orcid.org/0000-0003-0733-3847
Kikelomo Ololade WrightLagos State University Teaching Hospital, Lagos, Lagos State, Nigeria.
Aina Olufemi OdusolaLagos State University Teaching Hospital, Lagos, Lagos State, Nigeria.
Babafemi ThomasHealth Service Commission, Lagos, Lagos State, Nigeria.
Oluwatosin AdeyemiLagos State University Teaching Hospital, Lagos, Lagos State, Nigeria.
Abimbola BowaleMainland Hospital, Yaba, Lagos, Nigeria.
Olusola AdejumoMainland Hospital, Yaba, Lagos, Nigeria.
Ayodeji FalanaMainland Hospital, Yaba, Lagos, Nigeria.
Ismail Abdus-SalamLagos State Ministry of Health, Lagos, Nigeria.
Olusegun OgboyeLagos State Ministry of Health, Lagos, Nigeria.
Akin OsibogunCollege of Medicine, University of Lagos, Lagos, Nigeria.
Akin AbayomiLagos State Ministry of Health, Lagos, Nigeria.
Lagos State University Teaching Hospital · NGLagos State Health Service Commission · NGUniversity of Lagos · NG

Funding

Lagos State Government NA
6 · The paper itself

Abstract

backgroundCoronavirus disease once thought to be a respiratory infection is now recognised as a multi-system disease affecting the respiratory, cardiovascular, gastrointestinal, neurological, immune, and hematopoietic systems. An emerging body of evidence suggests the persistence of COVID-19 symptoms of varying patterns among some survivors. This study aimed to describe persistent symptoms in COVID-19 survivors and investigate possible risk factors for these persistent symptoms.

methodsThe study used a retrospective study design. The study population comprised of discharged COVID-19 patients. Demographic information, days since discharge, comorbidities, and persistent COVID-19 like symptoms were assessed in patients attending the COVID-19 outpatient clinic in Lagos State. Statistical analysis was done using STATA 15.0 software (StataCorp Texas) with significance placed at p-value < 0.05.

resultsA total of 274 patients were enrolled in the study. A majority were within the age group > 35 to ≤49 years (38.3%), and male (66.1%). More than one-third (40.9%) had persistent COVID-19 symptoms after discharge, and 19.7% had more than three persistent COVID-like symptoms. The most persistent COVID-like symptoms experienced were easy fatigability (12.8%), headaches (12.8%), and chest pain (9.8%). Symptomatic COVID-19 disease with moderate severity compared to mild severity was a predictor of persistent COVID-like symptoms after discharge (p < 0.05).

conclusionFindings from this study suggests that patients who recovered from COVID-19 disease may still experience COVID-19 like symptoms, particularly fatigue and headaches. Therefore, careful monitoring should be in place after discharge to help mitigate the effects of these symptoms and improve the quality of life of COVID-19 survivors.

Indexed as

SurvivorsAdultChest PainComorbidityCOVID-19FatigueFemaleHeadacheHumansMaleMiddle AgedNigeriaPatient DischargePost-Acute COVID-19 SyndromeQuality of LifeRetrospective StudiesCOVID-19Persistent symptomsSurvivors

Identifiers

PMID33765941
PMCPMC7993075
OpenAlexW3138795269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.