Evidence map›Paper›PMID 33765516›Full record

ArticleThe International journal on drug policy2021

A qualitative assessment of discharge against medical advice among patients hospitalized for injection-related bacterial infections in West Virginia.

R A Pollini, C E Paquette, T Drvar, P Marshalek, M Ang-Rabanes, J Feinberg, M W Haut

Abstract read
In one paragraph

Article in The International journal on drug policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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  8. Examining geographic disparities in access to no-cost naloxone in North Carolina: A cross-sectional survey of naloxone distribution programs.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

R A PolliniDepartment of Behavioral Medicine & Psychiatry, School of Medicine, West Virginia University, United States; Department of Epidemiology, School of Public Health, West Virginia University, United States. Electronic address: robin.pollini@hsc.wvu.edu.
C E PaquetteDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, United States.
T DrvarDepartment of Behavioral Medicine & Psychiatry, School of Medicine, West Virginia University, United States.
P MarshalekDepartment of Behavioral Medicine & Psychiatry, School of Medicine, West Virginia University, United States.
M Ang-RabanesDepartment of Behavioral Medicine & Psychiatry, School of Medicine, West Virginia University, United States.
J FeinbergDepartment of Behavioral Medicine & Psychiatry, School of Medicine, West Virginia University, United States.
M W HautDepartment of Behavioral Medicine & Psychiatry, School of Medicine, West Virginia University, United States; Department of Neurology, School of Medicine, West Virginia University, United States; Department of Neuroscience, School of Medicine, West Virginia University, United States; Department of Radiology, School of Medicine, West Virginia University, United States.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

backgroundThe incidence of infective endocarditis (IE) and other systemic bacterial infections is increasing, and people who inject drugs (PWID) have higher rates of discharge against medical advice (AMA) for these infections than patients whose infections are not injection-related. In this study, we characterize factors that contribute to AMA hospital discharge among PWID.

methodsWe conducted qualitative interviews with twenty PWID hospitalized with serious injection-related bacterial infections in West Virginia. Participants completed a brief survey and in-depth qualitative interview. Interviews were recorded and transcribed verbatim and analyzed using a codebook developed based on deductive and inductive thematic analysis. We also conducted medical records abstraction and used descriptive statistics to summarize medical and survey data.

resultsAverage age was 34 years, 55% were female, 95% identified as white, and 75% had a primary diagnosis of IE. Drugs injected prior to hospitalization were methamphetamine (60%), prescription opioids (38%), and/or heroin/fentanyl (25%). Participants cited multiple contributors to AMA discharge including negative interactions with hospital staff that they perceived as stigmatizing, including being searched or monitored for illicit drug use; inadequate management of pain and withdrawal; boredom and confinement during lengthy hospitalizations; and isolation from family and other social supports.

conclusionWe identified multiple factors contributing to AMA discharge that are amenable to intervention. Given the significant morbidity, mortality, and financial costs associated with hospitalizing PWID for serious injection-related bacterial infections, hospitals should be highly motivated to develop and test interventions designed to improve outcomes among these patients.

Indexed as

Bacterial InfectionsSubstance Abuse, IntravenousAdultFemaleFentanylHumansPatient DischargeWest VirginiaFentanylAMA dischargeEndocarditisInjection drug usePeople who inject drugs

Identifiers

PMID33765516
PMCPMC8373672

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.