Evidence map›Paper›PMID 33765455›Full record

SynthesisThe Lancet. Public health2021

Incidence and prevalence of tuberculosis in incarcerated populations: a systematic review and meta-analysis.

Olivia Cords, Leonardo Martinez, Joshua L Warren, Jamieson Michael O'Marr, Katharine S Walter, Ted Cohen, Jimmy Zheng, Albert I Ko, Julio Croda, Jason R Andrews

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Lancet. Public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Number needed to screen for TB in clinical, structural or occupational risk groups.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Pooled it
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Hidden burden of leprosy in incarcerated populations in northeast Brazil: active case detection and serological assessment.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Infection Control in Carceral Facilities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  16. Article
  17. Review
  18. Article
  19. Reinforcement Learning-Based Control of Epidemics on Networks of Communities and Correctional Facilities.Medical decision making : an international journal of the Society for Medical Decision Making · 2026
    Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Olivia CordsDivision of Infectious Diseases and Geographic Medicine, Stanford, CA, USA.
Leonardo MartinezDivision of Infectious Diseases and Geographic Medicine, Stanford, CA, USA; Department of Epidemiology, School of Public Health, Boston University, Boston, MA, USA. Electronic address: leomarti@bu.edu.
Joshua L WarrenDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Jamieson Michael O'MarrDivision of Infectious Diseases and Geographic Medicine, Stanford, CA, USA; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Katharine S WalterDivision of Infectious Diseases and Geographic Medicine, Stanford, CA, USA.
Ted CohenDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Jimmy ZhengStanford University School of Medicine, Stanford, CA, USA.
Albert I KoDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA; Oswaldo Cruz Foundation, Salvador, Brazil.
Julio CrodaDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA; Universidade Federal de Mato Grosso do Sul, Faculdade de Medicina, Campo Grande, Mato Grosso do Sul, Brazil; Fundação Oswaldo Cruz, Campo Grande, Mato Grosso do Sul, Brazil.
Jason R AndrewsDivision of Infectious Diseases and Geographic Medicine, Stanford, CA, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Strategies for tuberculosis control in prisonsR01AI130058 · NIAID · STANFORD UNIVERSITY · PI Jason Randolph Andrews, Julio Henrique Rosa Croda · 2017 to 2026
$5.8M
Global Epidemiology of Infectious DiseasesT32AI052073 · NIAID · STANFORD UNIVERSITY · PI Angelle Desiree LaBeaud, Stephen Patrick Luby · 2003 to 2026
$4.2M
UC Davis DVM/PhD Medical Scientist Training ProgramT32GM136559 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Xinbin Chen, Bethany Paige Cummings · 2020 to 2026
$2.2M
Identifying effective and efficient approaches to tuberculosis screening in BrazilianprisonsK01AI156022 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MARTINEZ, LEONARDO · 2021 to 2025
$640k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS K01 AI156022NIAID NIH HHS R01 AI130058NIAID NIH HHS T32 AI052073NIGMS NIH HHS T32 GM136559
6 · The paper itself

Abstract

backgroundPrisons are recognised as high-risk environments for tuberculosis, but there has been little systematic investigation of the global and regional incidence and prevalence of tuberculosis, and its determinants, in prisons. We did a systematic review and meta-analysis to assess the incidence and prevalence of tuberculosis in incarcerated populations by geographical region.

methodsIn this systematic review and meta-analysis, we searched MEDLINE, Embase, Web of Knowledge, and the LILACS electronic database from Jan 1, 1980, to Nov 15, 2020, for cross-sectional and cohort studies reporting the incidence of Mycobacterium tuberculosis infection, incidence of tuberculosis, or prevalence of tuberculosis among incarcerated individuals in all geographical regions. We extracted data from individual studies, and calculated pooled estimates of incidence and prevalence through hierarchical Bayesian meta-regression modelling. We also did subgroup analyses by region. Incidence rate ratios between prisons and the general population were calculated by dividing the incidence of tuberculosis in prisons by WHO estimates of the national population-level incidence.

findingsWe identified 159 relevant studies; 11 investigated the incidence of M tuberculosis infection (n=16 318), 51 investigated the incidence of tuberculosis (n=1 858 323), and 106 investigated the prevalence of tuberculosis (n=6 727 513) in incarcerated populations. The overall pooled incidence of M tuberculosis infection among prisoners was 15·0 (95% credible interval [CrI] 3·8-41·6) per 100 person-years. The incidence of tuberculosis (per 100 000 person-years) among prisoners was highest in studies from the WHO African (2190 [95% CrI 810-4840] cases) and South-East Asia (1550 [240-5300] cases) regions and in South America (970 [460-1860] cases), and lowest in North America (30 [20-50] cases) and the WHO Eastern Mediterranean region (270 [50-880] cases). The prevalence of tuberculosis was greater than 1000 per 100 000 prisoners in all global regions except for North America and the Western Pacific, and highest in the WHO South-East Asia region (1810 [95% CrI 670-4000] cases per 100 000 prisoners). The incidence rate ratio between prisons and the general population was much higher in South America (26·9; 95% CrI 17·1-40·1) than in other regions, but was nevertheless higher than ten in the WHO African (12·6; 6·2-22·3), Eastern Mediterranean (15·6; 6·5-32·5), and South-East Asia (11·7; 4·1-27·1) regions.

interpretationGlobally, people in prison are at high risk of contracting M tuberculosis infection and developing tuberculosis, with consistent disparities between prisons and the general population across regions. Tuberculosis control programmes should prioritise preventive interventions among incarcerated populations.

fundingUS National Institutes of Health.

Indexed as

Global HealthHumansIncidencePrevalencePrisonersTuberculosis

Identifiers

PMID33765455
PMCPMC8168455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.