ArticleClinical oral investigations2021
Effect of ionizing radiation and cariogenic biofilm challenge on root-dentin caries.
Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Direct radiation damage to human tooth under IMRT for head and neck cancer: physicochemical evidence supporting a non-salivary mechanism for radiation-related caries.Radiation and environmental biophysics · 2026Article
- Assessment of multispecies biofilm growth on root canal dentin under different radiation therapy regimens.Clinical oral investigations · 2024Article
- Heavy Ion Radiation Directly Induced the Shift of Oral Microbiota and Increased the Cariogenicity ofMicrobiology spectrum · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the effect of ionizing radiation and cariogenic biofilm challenge using two continuous flow models, normal and reduced salivary flow, on the development of initial root-dentin caries lesions. MATERIALS AND
methodsMicrocosm biofilms were grown under two salivary flow rates (0.06 and 0.03 mL min
resultsWith normal salivary flow, FTIR revealed an increase in the organic matrix (amide III) and a decrease in the mineral phase (ν
conclusionsInitial caries lesions differed between non-irradiated and irradiated dentin and between normal and reduced salivary flow rates. Significant mineral loss with exposure of the organic matrix and low mineral density were observed for irradiated dentin with a reduced salivary flow rate. CLINICAL RELEVANCE: Ionizing radiation associated with a reduced salivary flow rate enhanced the progression of root-dentin caries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.