Evidence map›Paper›PMID 33764843›Full record

ArticleAutophagy2021

Long noncoding RNA (lncRNA)

Yuhao Luo, Siting Zheng, Qianying Wu, Jianhua Wu, Rui Zhou, Chunling Wang, Zhenzhen Wu, Xiaoxiang Rong, Na Huang, Li Sun and 4 more

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed, 4 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

153 citing papers in PubMed, 4 syntheses or guidelines pooled it, 228 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. The multifaceted role of 3-methyladenine in cancer therapy.Journal of physiology and biochemistry · 2026
    Review
  7. Review
  8. Article
  9. Article
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  11. The ATG14: multi-layer autophagy control and an emerging therapeutic target in cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
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  13. Article
  14. Review
  15. Article
  16. Article
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  20. Article

93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yuhao LuoDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Siting ZhengDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Qianying WuDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jianhua WuDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Rui ZhouDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Chunling WangDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Zhenzhen WuDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xiaoxiang RongDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Na HuangDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Li SunDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jianping BinDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Yulin LiaoDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Min ShiDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Wangjun LiaoDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID 0000-0002-1364-8442
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy is currently the main treatment for unresectable or advanced postoperative gastric cancers. However, its efficacy is negatively affected by the occurrence of chemoresistance, which severely affects patient prognosis. Recently, dysregulation in autophagy has been suggested as a potential mechanism for chemoresistence, and long noncoding RNA (lncRNA) also shows its regulatory role in cancer drug resistance. Using RNA sequencing, we found that lncRNA

Indexed as

MicroRNAsRNA, Long NoncodingStomach NeoplasmsAutophagyCell Line, TumorDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHumansIn Situ Hybridization, FluorescenceMicroRNAsMIRN188 microRNA, humanRNA, Long NoncodingATG14autophagychemotherapy resistanceEIF3J-DT; gastric cancer

Identifiers

PMID33764843
PMCPMC8726636
OpenAlexW3138485468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.