ArticleJournal of cachexia, sarcopenia and muscle2021
Frailty in patients undergoing transcatheter aortic valve replacement: prognostic value of the Geriatric Nutritional Risk Index.
Article in Journal of cachexia, sarcopenia and muscle, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- The association between geriatric nutritional risk index and mortality risk of patients after transcatheter aortic valve replacement: a meta-analysis.Frontiers in nutrition · 2026Pooled it
- Malnutrition Predicts Adverse Outcomes After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.Anatolian journal of cardiology · 2023Pooled it
- Prognostic Significance of Nutrition-Associated Markers in Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-Analysis.Arquivos brasileiros de cardiologia · 2023Pooled it
- Geriatric nutritional risk index associated to long-term prognosis and length of hospitalization in the contemporary transcatheter aortic valve replacement era.Journal of geriatric cardiology : JGC · 2026Article
- Article
- Association between Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in centenarians, with a focus on nonlinear and threshold effects: a multi-method observational study.Frontiers in nutrition · 2026Article
- Association of the Geriatric Nutritional Risk Index With Prognosis in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.Immunity, inflammation and disease · 2026Article
- Association Between the Geriatric Nutritional Risk Index and All-Cause Mortality in Elderly Patients with Acute Ischemic Stroke After Intravenous Thrombolysis.International journal of general medicine · 2026Article
- Geriatric nutritional risk index improves risk scoring for mortality after TAVR compared to established scores.Frontiers in cardiovascular medicine · 2026Article
- Predictors of Length of Stay in Hospital After Transcatheter Aortic Valve Replacement: Impact of Naples Prognostic Score.Medicina (Kaunas, Lithuania) · 2025Article
- Association between geriatric nutritional risk index and In-Hospital mortality in acute aortic dissection patients: a retrospective cohort study.BMC cardiovascular disorders · 2025Article
- Osteosarcopenia in older adults undergoing transcatheter aortic valve replacement: A narrative review of mortality and frailty implications.World journal of cardiology · 2025Review
- Association between the geriatric nutritional risk index with the risk of frailty and mortality in the elderly population.Scientific reports · 2025Article
- [Construction of a mixed valvular heart disease-related age-adjusted comorbidity index and its predictive value for patient prognosis].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Article
- Association Between the Malnutrition Status and All-Cause Mortality in Patients With Moderate and Severe Aortic Stenosis: A Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- The joint role of systemic immune-inflammation index and geriatric nutritional risk index in cancer survivors and their impact on all-cause mortality.Frontiers in nutrition · 2025Article
- Association of inflammation geriatric nutritional risk index with all-cause and CVD mortality in patients with osteoarthritis.Frontiers in nutrition · 2025Article
- Prevalence and Prognostic Significance of Malnutrition Risk in Patients With Valvular Heart Disease.JACC. Advances · 2025Article
- Cardiac rehabilitation for TAVR patients: mechanisms, current status, and future directions.Frontiers in cardiovascular medicine · 2025Review
- Comparison of the Value of Four Objective Nutritional Indices in Assessing the Long-Term Prognosis of Elderly Patients with Heart Failure with Preserved Ejection Fraction.Reviews in cardiovascular medicine · 2024Article
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition is a hallmark of frailty, is common among elderly patients, and is a predictor of poor outcomes in patients with severe symptomatic aortic stenosis (AS). The Geriatric Nutritional Risk Index (GNRI) is a simple and well-established screening tool to predict the risk of morbidity and mortality in elderly patients. In this study, we evaluated whether GNRI may be used in the risk stratification and management of patients undergoing transcatheter aortic valve replacement (TAVR).
methodsPatients with symptomatic severe AS (n = 953) who underwent transfemoral TAVR at the University Hospital Schleswig-Holstein Kiel, Germany, between 2010 and 2019 (development cohort) were divided into two groups: normal GNRI ≥ 98 (no nutrition-related risk; n = 618) versus low GNRI < 98 (at nutrition-related risk; n = 335). The results were validated in an independent (validation) cohort from another high-volume TAVR centre (n = 977).
resultsThe low-GNRI group had a higher proportion of female patients (59.1% vs. 52.1%), higher median age (82.9 vs. 81.8 years), prevalence of atrial fibrillation (50.4% vs. 40.0%), median logistic EuroSCORE (17.5% vs. 15.0%) and impaired left ventricular function (<35%: 10.7% vs. 6.8%), lower median estimated glomerular filtration rate (50 vs. 57 mL/min/1.73 m
conclusionsLow GNRI score was associated with an increased risk of all-cause mortality in patients undergoing TAVR, implying that this vulnerable group may benefit from improved preventive measures.
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