Evidence map›Paper›PMID 33764427›Full record

ArticleJournal of biomechanical engineering2021

Blood Flow Velocimetry in a Microchannel During Coagulation Using Particle Image Velocimetry and Wavelet-Based Optical Flow Velocimetry.

E Kucukal, Y Man, Umut A Gurkan, B E Schmidt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomechanical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

E KucukalDepartment of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106.
Y ManDepartment of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106.
Umut A GurkanWarren E. Rupp Associate Professor Department of Mechanical and Aerospace Engineering, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106; Department of Biomedical Engineering, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.
B E SchmidtDepartment of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106.

Funding

Standardized Monitoring of Cellular Adhesion to Improve Clinical Care in Sickle Cell DiseaseR01HL133574 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI GURKAN, UMUT A., LITTLE, JANE · 2016 to 2020
$2.0M
NHLBI NIH HHS R01 HL133574
6 · The paper itself

Abstract

This article describes novel measurements of the velocity of whole blood flow in a microchannel during coagulation. The blood is imaged volumetrically using a simple optical setup involving a white light source and a microscope camera. The images are processed using particle image velocimetry (PIV) and wavelet-based optical flow velocimetry (wOFV), both of which use images of individual blood cells as flow tracers. Measurements of several clinically relevant parameters such as the clotting time, decay rate, and blockage ratio are computed. The high-resolution wOFV results yield highly detailed information regarding thrombus formation and corresponding flow evolution that is the first of its kind.

Indexed as

RheologyBlood CoagulationBlood Flow VelocityHumansLightParticle Size

Identifiers

PMID33764427
PMCPMC8299809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.