Evidence map›Paper›PMID 33764425›Full record

ArticleJAMA network open2021

Patient-Reported Opioid Consumption and Pain Intensity After Common Orthopedic and Urologic Surgical Procedures With Use of an Automated Text Messaging System.

Anish K Agarwal, Daniel Lee, Zarina Ali, Brian Sennett, Ruiying Xiong, Jessica Hemmons, Evan Spencer, Dina Abdel-Rahman, Rachel Kleinman, Hannah Lacko and 5 more

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05169281 (Cluster Randomized Trial of a Mailed At-home Kit on Disposal of Unused Opioids Following Surgery), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05169281 nacompletednot on this map

Cluster Randomized Trial of a Mailed At-home Kit on Disposal of Unused Opioids Following Surgery

TypeinterventionalSponsorUniversity of PennsylvaniaRan2021 to 2021Enrolled657ConditionsOrthopedic Surgery, Neurosurgery, Surgery, Opioid UseArmsMedication Disposal Packet
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Identifying Patient Characteristics Associated With Opioid Use to Inform Surgical Pain Management.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Clinician Views of an Opioid Prescribing Report with Peer Comparisons and Patient-Reported Outcomes.American journal of medical quality : the official journal of the American College of Medical Quality
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Anish K AgarwalDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia.
Daniel LeeLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.
Zarina AliLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.
Brian SennettDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia.
Ruiying XiongDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia.
Jessica HemmonsDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia.
Evan SpencerDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia.
Dina Abdel-RahmanDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia.
Rachel KleinmanDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia.
Hannah LackoDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia.
Annamarie HoranDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia.
Mary DooleyDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia.
Eric HumeLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.
Samir MehtaDepartment of Orthopaedic Surgery, University of Pennsylvania, Philadelphia.
M Kit DelgadoDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia.
University of Pennsylvania · USUniversity of Pennsylvania Health System · US

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Learning Health Systems Mentored Career Development ProgramK12HS026372 · AHRQ · UNIVERSITY OF PENNSYLVANIA · PI ASCH, DAVID A, LANE-FALL, MEGHAN BROOKS · 2018 to 2022
$3.2M
AHRQ HHS K12 HS026372NCATS NIH HHS UL1 TR001878
6 · The paper itself

Abstract

Importance: Surgeons must balance management of acute postoperative pain with opioid stewardship. Patient-centered methods that immediately evaluate pain and opioid consumption can be used to guide prescribing and shared decision-making. Objective: To assess the difference between the number of opioid tablets prescribed and the self-reported number of tablets taken as well as self-reported pain intensity and ability to manage pain after orthopedic and urologic procedures with use of an automated text messaging system. Design, Setting, and Participants: This quality improvement study was conducted at a large, urban academic health care system in Pennsylvania. Adult patients (aged ≥18 years) who underwent orthopedic and urologic procedures and received postoperative prescriptions for opioids were included. Data were collected prospectively using automated text messaging until postoperative day 28, from May 1 to December 31, 2019. Main Outcomes and Measures: The primary outcome was the difference between the number of opioid tablets prescribed and the patient-reported number of tablets taken (in oxycodone 5-mg tablet equivalents). Secondary outcomes were self-reported pain intensity (on a scale of 0-10, with 10 being the highest level of pain) and ability to manage pain (on a scale of 0-10, with 10 representing very able to control pain) after orthopedic and urologic procedures. Results: Of the 919 study participants, 742 (80.7%) underwent orthopedic procedures and 177 (19.2%) underwent urologic procedures. Among those who underwent orthopedic procedures, 384 (51.8%) were women, 491 (66.7%) were White, and the median age was 48 years (interquartile range [IQR], 32-61 years); 514 (69.8%) had an outpatient procedure. Among those who underwent urologic procedures, 145 (84.8%) were men, 138 (80.7%) were White, and the median age was 56 years (IQR, 40-67 years); 106 (62%) had an outpatient procedure. The mean (SD) pain score on day 4 after orthopedic procedures was 4.72 (2.54), with a mean (SD) change by day 21 of -0.40 (1.91). The mean (SD) ability to manage pain score on day 4 was 7.32 (2.59), with a mean (SD) change of -0.80 (2.72) by day 21. The mean (SD) pain score on day 4 after urologic procedures was 3.48 (2.43), with a mean (SD) change by day 21 of -1.50 (2.12). The mean (SD) ability to manage pain score on day 4 was 7.34 (2.81), with a mean (SD) change of 0.80 (1.75) by day 14. The median quantity of opioids prescribed for patients who underwent orthopedic procedures was high compared with self-reported consumption (20 tablets [IQR, 15-30 tablets] vs 6 tablets used [IQR, 0-14 tablets]), similar to findings for patients who underwent urologic procedures (7 tablets [IQR, 5-10 tablets] vs 1 tablet used [IQR, 0-4 tablets]). Over the study period, 9452 of 15 581 total tablets prescribed (60.7%) were unused. A total of 589 patients (64.1%) used less than half of the amount prescribed, and 256 patients (27.8%) did not use any opioids (179 [24.1%] who underwent orthopedic procedures and 77 [43.5%] who underwent urologic procedures). Conclusions and Relevance: In this quality improvement study of adult patients reporting use of opioids after common orthopedic and urologic surgical procedures through a text messaging system, the quantities of opioids prescribed and the quantity consumed differed. Patient-reported data collected through text messaging may support clinicians in tailoring prescriptions and guide shared decision-making to limit excess quantities of prescribed opioids.

Indexed as

Patient Reported Outcome MeasuresQuality ImprovementText MessagingAdultAgedAnalgesics, OpioidFemaleHumansMaleMiddle AgedOrthopedic ProceduresPostoperative PainUrologic Surgical ProceduresAnalgesics, Opioid

Identifiers

PMID33764425
PMCPMC7994954
OpenAlexW3137858006

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.