Evidence map›Paper›PMID 33764079›Full record

ArticleBehavioral neuroscience2021

The stressed orbitofrontal cortex.

Michelle K Sequeira, Shannon L Gourley

Open access · hybridAbstract read
In one paragraph

Article in Behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michelle K SequeiraGraduate Training Program in Neuroscience.ORCID 0000-0003-4450-414X
Shannon L GourleyGraduate Training Program in Neuroscience.
Neuroscience Institute · IT

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
The Impact of Oxytocin on the Neural Representation Social Stimuli P50MH100023 · NIMH · EMORY UNIVERSITY · PI SANCHEZ, MAR M · 2013 to 2022
$21.8M
Training In Systems And Integrative Biology NeuroscienceT32NS096050 · NINDS · EMORY UNIVERSITY · PI Yoland Smith · 2016 to 2026
$3.9M
Orbitofrontal cortical coordination of action-consequence decision makingR01MH117103 · NIMH · EMORY UNIVERSITY · PI GOURLEY, SHANNON LEIGH · 2018 to 2022
$2.3M
Integrated mechanisms for orbitofrontal cortical control of memory and choiceR37MH117103 · NIMH · EMORY UNIVERSITY · PI Shannon Leigh Gourley · 2024 to 2026
$2.0M
Defining the role of glucocorticoid-related dendritic spine plasticity in cocaine-induced habitsF31DA051184 · NIDA · EMORY UNIVERSITY · PI SEQUEIRA, MICHELLE KATHRYN · 2020 to 2022
$126k
NIDA NIH HHS F31 DA051184NIH HHS P51 OD011132NIMH NIH HHS P50 MH100023NIMH NIH HHS R01 MH117103NIMH NIH HHS R37 MH117103NINDS NIH HHS T32 NS096050
6 · The paper itself

Abstract

Stressor exposure causes dendritic remodeling on excitatory neurons in multiple regions of the brain, including the orbitofrontal cortex (OFC). Additionally, stressor and exogenous stress hormone exposure impair cognitive functions that are dependent on the OFC. For this Special Issue on the OFC, we summarize current literature regarding how stress-prenatal, postnatal, and even inter-generational-affects OFC neuron structure in rodents. We discuss dendrite structure, dendritic spines, and gene expression. We aim to provide a focused resource for those interested in how stressors impact this heterogeneous brain region. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

CognitionPrefrontal CortexFemaleHumansNeuronsPregnancy

Identifiers

PMID33764079
PMCPMC8284911
OpenAlexW3136791783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.