ArticleAdvanced materials (Deerfield Beach, Fla.)2021
Degradable and Removable Tough Adhesive Hydrogels.
Article in Advanced materials (Deerfield Beach, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Emerging biologic augmentation strategies for meniscal repair: a systematic review.BMC musculoskeletal disorders · 2024Pooled it
- Antifibrotic hydrogel strategies for scarless tissue regeneration: mechanisms, design, and application.Bioactive materials · 2027Review
- Spatiotemporally responsive hybrid hydrogels for sequential therapy and visualized monitoring of multidrug-resistant bacterial wound infections.Bioactive materials · 2026Article
- Next-Generation Hydrogel Skin Adhesives: From Bioinspired Adhesion Chemistry to Regenerative Wound Interfaces.Advanced healthcare materials · 2026Review
- A versatile and simple rectangular-topology strategy enables robust hydrogels.Nature communications · 2026Article
- Biomass-Derived Hydrogels for Load-Bearing Connective Tissue Repair: Integrative Reinforcement, Bio-Functional Design, and Emerging Pathways Toward Clinical Translation.Advanced healthcare materials · 2026Review
- A sequential dual-drug delivery system for multi-target inhibition of subretinal fibrosis.Journal of nanobiotechnology · 2026Article
- Tough adhesive bilayer hydrogels.Cell reports. Physical science · 2026Article
- Hemostatic Tough Adhesives seal tissue and control hemorrhage.Nature communications · 2026Article
- On-Demand Chemically Degradable Hydrogels for Biological Applications.Chembiochem : a European journal of chemical biology · 2026Review
- Biobased adhesive hydrogels for wound management and tissue repair: From materials to advanced applications.APL bioengineering · 2026Review
- A dynamically adaptive wet-adhesive Janus hydrogel patch for sutureless repair of spinal dural defects.Bioactive materials · 2026Article
- Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026Review
- Trace-stimuli-triggered controlled degradation for hydrogel adhesives.National science review · 2026Article
- Highly tough and conformal silk-based adhesive patches for sutureless repair of gastrointestinal and peripheral nerve defects.Bioactive materials · 2025Article
- Decellularized extracellular matrix bio-patch with strong and biodegradable wet adhesive interface for sutureless soft tissue defect repair.Journal of nanobiotechnology · 2025Article
- Mechanically Active and Antimicrobial Wound Closure Using an Adhesive Hydrogel-Elastomer.ACS pharmacology & translational science · 2025Article
- Dynamic-covalent hybrid hydrogels with cartilaginous immune microenvironment temporally regulating meniscus regeneration.Bioactive materials · 2025Article
- Resolving hyperelasticity-adhesiveness conflict in polymer networks by in situ constructing mechanical heterogeneities.Nature communications · 2025Article
- Polymer oxidation: A strategy for the controlled degradation of injectable cryogels.Materials today. Bio · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The development of tough adhesive hydrogels has enabled unprecedented adhesion to wet and moving tissue surfaces throughout the body, but they are typically composed of nondegradable components. Here, a family of degradable tough adhesive hydrogels containing ≈90% water by incorporating covalently networked degradable crosslinkers and hydrolyzable ionically crosslinked main-chain polymers is developed. Mechanical toughness, adhesion, and degradation of these new formulations are tested in both accelerated in vitro conditions and up to 16 weeks in vivo. These degradable tough adhesives are engineered with equivalent mechanical and adhesive properties to nondegradable tough adhesives, capable of achieving stretches >20 times their initial length, fracture energies >6 kJ m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.