Evidence map›Paper›PMID 33763654›Full record

ArticleCell reports. Medicine2021

Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack.

Weldy V Bonilla, Nicole Kirchhammer, Anna-Friederike Marx, Sandra M Kallert, Magdalena A Krzyzaniak, Min Lu, Stéphanie Darbre, Sarah Schmidt, Josipa Raguz, Ursula Berka and 10 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Chronic infection perturbs the affinity hierarchy of antiviral B cells.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  6. Article
  7. Article
  8. Orf virus-based vectors induce potent germinal center B cell, Tfh cell, and CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  9. Cancer vaccines: current status and future directions.Journal of hematology & oncology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Vaccine adjuvants for infectious disease in the clinic.Bioengineering & translational medicine · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Weldy V BonillaUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Nicole KirchhammerUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Anna-Friederike MarxUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Sandra M KallertUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Magdalena A KrzyzaniakUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Min LuUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Stéphanie DarbreDepartment of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Sarah SchmidtHookipa Pharma Inc., Vienna, Austria.
Josipa RaguzHookipa Pharma Inc., Vienna, Austria.
Ursula BerkaHookipa Pharma Inc., Vienna, Austria.
Ilena VincentiDepartment of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Mindaugas PauzuolisDepartment of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Romy KerberBernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Sabine HoepnerTumor Immunology, Department for BioMedical Research, University of Bern, Bern, Switzerland.
Stephan GüntherBernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Carsten MagnusInstitute of Virology, University of Zurich, Zurich, Switzerland.
Doron MerklerDepartment of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Klaus K OrlingerHookipa Pharma Inc., Vienna, Austria.
Alfred ZippeliusUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
Daniel D PinschewerUniversity of Basel, Department of Biomedicine, Basel, Switzerland.
University of Basel · CHUniversity of Geneva · CHBernhard Nocht Institute for Tropical Medicine · DEUniversity of Bern · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic vaccination regimens inducing clinically effective tumor-specific CD8

Indexed as

AlarminsAnimalsAntibodies, NeutralizingCancer VaccinesFemaleGene ExpressionGenetic EngineeringGenetic VectorsGuinea PigsImmunization, SecondaryImmunotherapyLymphocytic choriomeningitis virusMastocytomaMiceMice, Inbred C57BLPhylogenyAlarminsAntibodies, NeutralizingCancer Vaccinesanti-vector immunityarenavirusCD8 T cellslymphocytic choriomeningitis virusPichinde viruspre-existing immunitytherapeutic tumor vaccinetumor controlviral genealogy

Identifiers

PMID33763654
PMCPMC7974551
OpenAlexW3135147458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.