Trial reportCell reports. Medicine2021
Effects of
Trial report in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Effects of Probiotics on Preterm Infant Gut Microbiota Across Populations: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Bifidobacterium infantis as a probiotic in preterm infants: a systematic review and meta-analysis.Pediatric research · 2023Pooled it
- Pooled it
- Effect of Supplementation withNutrients · 2026Trial
- Neurodevelopment and Growth 2 Years After Probiotic Supplementation in Extremely Preterm Infants: A Randomised Trial.Acta paediatrica (Oslo, Norway : 1992) · 2025Trial
- Impact of Extreme Prematurity, Chorioamnionitis, and Sepsis on Neonatal Monocyte Characteristics and Functions.Journal of innate immunity · 2024Trial
- The preterm gut microbiota and administration routes of different probiotics: a randomized controlled trial.Pediatric research · 2023Trial
- Effect of single versus multistrain probiotic in extremely preterm infants: a randomised trial.BMJ open gastroenterology · 2022Trial
- Intestinal Microbial Composition of Children in a Randomized Controlled Trial of Probiotics to Treat Acute Gastroenteritis.Frontiers in cellular and infection microbiology · 2022Trial
- Trial
- Supplementation with long-chain polyunsaturated fatty acids to extremely preterm infants associates with development of the intestinal microbiota.Pediatric research · 2026Article
- Mother-to-offspring microbial vertical transmission: timing, determinants, and impact on offspring susceptibility to gastrointestinal diseases.Medical review (2021) · 2026Review
- Article
- Gut microbiota-dependent protection by Lactobacillus reuteri against renal injury in brain-dead rats.Scientific reports · 2026Article
- Probiotic novel strain Lactobacillus reuteri MRD01 alleviates dextran sulfate sodium-induced colitis in male mice by promoting intestinal barrier integrity.Antonie van Leeuwenhoek · 2026Article
- Biofilm state Limosilactobacillus reuteri modulates aryl hydrocarbon receptor activity and suppresses experimental necrotizing enterocolitis.Pediatric research · 2026Article
- Temporal dynamics of gut microbiota and virome in preterm infants: insights from longitudinal metagenomic analysis.Frontiers in cellular and infection microbiology · 2026Article
- Dynamics of postnatal upper airway bacteria colonization in preterm infants <1000g and bronchopulmonary dysplasia.Scientific reports · 2025Article
- The microbiome's hidden influence: preclinical insights into inflammatory responses in necrotizing enterocolitis.Seminars in immunopathology · 2025Review
- Formation of gut microbiota and application of microecological regulators in children.Translational pediatrics · 2025Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extremely low birth weight (ELBW) infants often develop an altered gut microbiota composition, which is related to clinical complications, such as necrotizing enterocolitis and sepsis. Probiotic supplementation may reduce these complications, and modulation of the gut microbiome is a potential mechanism underlying the probiotic effectiveness. In a randomized, double-blind, placebo-controlled trial, we assessed the effect of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.