Evidence map›Paper›PMID 33763638›Full record

ArticleiScience2021

Hypoxia-activated probe for NIR fluorescence and photoacoustic dual-mode tumor imaging.

Meng Li, Huan Li, Qian Wu, Niu Niu, Jiachang Huang, Lingmin Zhang, Ying Li, Dong Wang, Ben Zhong Tang

Abstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  6. Recent advances in aggregation-induced emission luminogens in photoacoustic imaging.European journal of nuclear medicine and molecular imaging · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meng LiCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China.
Huan LiKey Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, P. R. China.
Qian WuCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China.
Niu NiuCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China.
Jiachang HuangCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China.
Lingmin ZhangKey Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, P. R. China.
Ying LiCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China.
Dong WangCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. China.
Ben Zhong TangDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Construction of tumor microenvironment responsive probe with more than one imaging modality, in particular toward hypoxia of solid tumors, is an appealing yet significantly challenging task. In this work, we designed a hypoxia-activated probe TBTO (Triphenylamine-Benzothiadiazole-Triphenylamine derivative featuring four diethylamino N-Oxide groups) for

Indexed as

Medical ImagingOptical ImagingOptical MaterialsOptical Property

Identifiers

PMID33763638
PMCPMC7973868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.