Evidence map›Paper›PMID 33763620›Full record

ArticleContemporary clinical trials communications2021

Mixed-methods trial of a phosphatidylethanol-based contingency management intervention to initiate and maintain alcohol abstinence in formerly homeless adults with alcohol use disorders.

Elizabeth R Fraser, Nathalie Hill-Kapturczak, Julianne Jett, Rachael Beck, Oladunni Oluwoye, Liat S Kriegel, Karl C Alcover, Sterling McPherson, Leopoldo J Cabassa, Martin Javors and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Elizabeth R FraserBehavioral Health Innovations, Washington State University, Spokane, WA, USA.
Nathalie Hill-KapturczakBiological Psychiatry Analytical Lab, University of Texas Health San Antonio, San Antonio, TX, USA.
Julianne JettBehavioral Health Innovations, Washington State University, Spokane, WA, USA.
Rachael BeckBehavioral Health Innovations, Washington State University, Spokane, WA, USA.
Oladunni OluwoyeBehavioral Health Innovations, Washington State University, Spokane, WA, USA.
Liat S KriegelBehavioral Health Innovations, Washington State University, Spokane, WA, USA.
Karl C AlcoverDepartment of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Sterling McPhersonElson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
Leopoldo J CabassaBrown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.
Martin JavorsBiological Psychiatry Analytical Lab, University of Texas Health San Antonio, San Antonio, TX, USA.
Michael G McDonellBehavioral Health Innovations, Washington State University, Spokane, WA, USA.
Washington State University Spokane · USThe University of Texas Health Science Center at San Antonio · USUniformed Services University of the Health Sciences · USWashington University in St. Louis · US

Funding

Novel EtG BasedContingency Management for Alcohol in the Severely Mentally IllR01AA020248 · NIAAA · WASHINGTON STATE UNIVERSITY · PI MCDONELL, MICHAEL G · 2012 to 2021
$4.6M
Peth-Based Contingency Management to Reduce Alcohol Use and Improve Housing OutcomesR21AA027045 · NIAAA · WASHINGTON STATE UNIVERSITY · PI MCDONELL, MICHAEL G · 2019 to 2020
$397k
NIAAA NIH HHS R01 AA020248NIAAA NIH HHS R21 AA027045
6 · The paper itself

Abstract

backgroundContingency management (CM) is an intervention where incentives are provided in exchange for biochemically confirmed alcohol abstinence. CM is effective at initiating alcohol abstinence, but it is less effective at maintaining long-term abstinence. Phosphatidylethanol (PEth), collected via a finger-stick, can detect alcohol use for 14-28 days. PEth allows for the development of a CM model that includes increasingly less frequent monitoring of abstinence to assist high risk groups, such as formerly homeless individuals, maintain long-term abstinence.

aimsInvestigate whether PEth-based CM intervention targeting alcohol abstinence in formerly homeless, currently housed individuals with alcohol use disorders is: (1) acceptable and feasible for housing program tenants and personnel; and is associated with increased (2) alcohol abstinence and (3) housing tenure.

methodsAcceptability and feasibility will be assessed using a QUAL+quant mixed-methods design using qualitative interviews and quantitative measures of satisfaction and attrition. Effectiveness will be evaluated through a randomized pilot trial of 50 study participants who will receive 6 months of either treatment as usual (TAU) including incentives (e.g., gift cards) for providing blood samples (Control Condition) or TAU and incentives for negative PEth results (PEth-CM Condition). Outcomes will be assessed during the intervention and at a three-month follow-up visit. The trial will be conducted via telehealth as a result of COVID-19. DISCUSSION: This protocol seeks to utilize a novel alcohol biomarker to evaluate the acceptability, feasibility, and initial effectiveness of a CM model that encourages long-term abstinence in a high-risk group.

Indexed as

alcohol treatmentAlcohol use disorderAUDContingency managementHomelessnessHousing programsPEthPhosphatidylethanol

Identifiers

PMID33763620
PMCPMC7973861
OpenAlexW3135176692

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.