Evidence map›Paper›PMID 33763492›Full record

ArticleJournal of immunology research2021

Prolactin Increases the Frequency of Follicular T Helper Cells with Enhanced IL21 Secretion and OX40 Expression in Lupus-Prone MRL/lpr Mice.

Yolanda P Alemán-García, Ricardo M Vaquero-García, Rocio Flores-Fernández, Ezequiel M Fuentes-Pananá, Patricia Gorocica-Rosete, Alberto Pizaña-Venegas, Luis Chávez-Sanchéz, Francico Blanco-Favela, María V Legorreta-Haquet, Adriana K Chávez-Rueda

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yolanda P Alemán-GarcíaUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.
Ricardo M Vaquero-GarcíaUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.
Rocio Flores-FernándezUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.
Ezequiel M Fuentes-PananáUnidad de Investigación en Virología y Cáncer, Hospital Infantil de México "Federico Gómez", Mexico.
Patricia Gorocica-RoseteDepartamento de Investigación en Bioquímica, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosió Villegas", Mexico.
Alberto Pizaña-VenegasUnidad de Investigación y Bioterio, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosió Villegas", Mexico.
Luis Chávez-SanchézUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.
Francico Blanco-FavelaUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.
María V Legorreta-HaquetUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.
Adriana K Chávez-RuedaUIM en Inmunología, Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, Mexico.ORCID https://orcid.org/0000-0002-9637-946X
Mexican Social Security Institute · MXInstituto Nacional de Enfermedades Respiratorias · MXHospital Infantil de México Federico Gómez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus is characterized by high levels of IgG class autoantibodies that contribute to the pathophysiology of the disease. The formation of these autoantibodies occurs in the germinal centers, where there is cooperation between follicular T helper cells (T

Indexed as

AnimalsAutoantibodiesCells, CulturedDisease Models, AnimalGerminal CenterHumansInterleukin-21InterleukinsLupus Erythematosus, SystemicLupus NephritisMiceMice, Inbred MRL lprProlactinReceptors, OX40Receptors, ProlactinSTAT3 Transcription FactorAutoantibodiesInterleukin-21InterleukinsProlactinReceptors, OX40Receptors, ProlactinSTAT3 Transcription FactorTNFRSF4 protein, human

Identifiers

PMID33763492
PMCPMC7963914
OpenAlexW3134270888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.