Evidence map›Paper›PMID 33763478›Full record

ArticleBioMed research international2021

Synthesis and Biological Evaluation of Novel Isoxazole-Amide Analogues as Anticancer and Antioxidant Agents.

Ahmad M Eid, Mohammed Hawash, Johnny Amer, Abdullah Jarrar, Samira Qadri, Iman Alnimer, Aya Sharaf, Raya Zalmoot, Osama Hammoudie, Saba Hameedi and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Synthesis,Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Anticancer, Free Radicals, and Digestive Enzyme Inhibitory Activities ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmad M EidDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.ORCID https://orcid.org/0000-0002-3425-1321
Mohammed HawashDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.ORCID https://orcid.org/0000-0001-5640-9700
Johnny AmerDepartment of Biomedical Sciences, Physiology, Pharmacology & Toxicology Division, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine, State of Palestine.
Abdullah JarrarDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Samira QadriDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Iman AlnimerDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Aya SharafDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Raya ZalmootDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Osama HammoudieDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Saba HameediDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus P.O. Box 7, 00970 Palestine, State of Palestine.
Ahmed MousaDepartment of Biomedical Sciences, Physiology, Pharmacology & Toxicology Division, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine, State of Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer now is one of the leading causes of mortality in the world. There has been a lot of effort to discover new anticarcinogenic agents that allow treatment with fewer side effects. A series of isoxazole-carboxamide derivatives (

Indexed as

AmidesAntineoplastic AgentsAntioxidantsIsoxazolesCell ProliferationDrug Screening Assays, AntitumorHeLa CellsHumansMCF-7 CellsNeoplasmsAmidesAntineoplastic AgentsAntioxidantsIsoxazoles

Identifiers

PMID33763478
PMCPMC7963892

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.